Clear cell adenocarcinoma of the ovary (OCC) is a chemo-resistant tumor with a relatively poor prognosis and is frequently associated with endometriosis. Although it is assumed that oxidative stress plays some role in the malignant transformation of this tumor, the characteristic molecular events leading to carcinogenesis remain unknown. In this study, an array-based comparative genomic hybridi...

The size of the ovary varies substantially among cattle. This variation may influence the potential of the ovary to produce follicles. In the present study, we examined whether a relationship exists between the weight of the ovary and the number of antral follicles >or=1 mm. Paired ovaries were obtained from Holstein x Japanese Black F1 heifers. Follicles were classified into three size categor...

BACKGROUND Extracapsular spread (ECS) in cervical lymph node metastases from head and neck squamous cell carcinoma (SCC) is regarded as an adverse prognostic factor and is often used to select patients who may benefit from adjuvant therapy. The prognostic value of ECS was evaluated for patients with oropharyngeal SCC (OPC; with known p16/human papillomavirus [HPV] status) and for patients with ...

The function of occludin (Occ) in the tight junction is undefined. To gain insight into its role in epithelial cell biology, occludin levels in Madin-Darby canine kidney II cells were suppressed by stably expressing short interfering RNA. Suppression of occludin was associated with a decrease in claudins-1 and -7 and an increase in claudins-3 and -4. Claudin-2 levels were unaffected. The tight ...

Distributed storage systems run transactions across machines to ensure serializability. Traditional protocols for distributed transactions are based on two-phase locking (2PL) or optimistic concurrency control (OCC). 2PL serializes transactions as soon as they conflict and OCC resorts to aborts, leaving many opportunities for concurrency on the table. This paper presents ROCOCO, a novel concurr...

Occludin is the first identified protein in the tight junction (TJ), but its function has remained for the most part obscure. TJs have been demonstrated to play important roles in the inner ear function, and occludin is expressed in all the epithelial TJs in the inner ear. Thus, we examined the inner ears of occludin-deficient (Occ(-/-)) mice. Although inner ears initially developed normally in...

CONTEXT A car occupant could be killed if struck by another occupant who was catapulted forward, backward, or sideways in a crash. OBJECTIVE To estimate the association between death of a car occupant (the target) and restraint use by other occupants. DESIGN Matched-pair cohort study comparing the outcomes of 2 target occupants in the same passenger car that crashed. SETTING United States...

The Optimistic Concurrency Control (OCC) method has been commonly used for in-memory databases to ensure transaction serializability — a transaction will be aborted if its read set has been changed during execution. This simple criterion to abort transactions causes a large proportion of false positives, leading to excessive transaction aborts. Transactions aborted false-positively (i.e. false ...

Heating, ventilation, air conditioning (HVAC) systems are significant consumers of energy, however building management systems do not typically operate them in accordance with occupant movements. Due to the delayed response of HVAC systems, prediction of occupant locations is necessary to maximize energy efficiency. In this paper we present two approaches to occupant location prediction based o...