Several modular processes are used to b u i l d r e l a t i o n s h i p s between a) two-dimensional regions and boundaries in a segmented image, and b) the hypothesized sur faces, volumes and ob jec ts of a three-dimensional wo r ld . A v a r i e t y of bottom-up and top-down s t ra teg ies coordinate the processes of SHAPE, PERSPECTIVE, SHADOW, and OCCLUSION to const ruct these r e l a t i on...

administration, most of the radioactivity appeared in the urine during the same period. Comparison of specific activities and differential distribution ra tios in organs after short-term and long-term ex periments with either drug indicated a selective uptake of radioactivity by liver, kidneys, and lungs immediately after administration. No selec tive uptake, however, was observed in any tissue...

Osteoblasts (OBs) and osteoclasts (OCs) are 2 major groups of bone cells. Their cell-to-cell interactions are important to ensure the continuity of the bone-remodeling process. Therefore, the present study was carried out to optimize an OB/OC co-culture system utilizing the human OB cell line hFOB 1.19 and OCs extracted from peripheral blood mononuclear cells (PBMNCs). It was a 2-step procedure...

As repor ted earlier 1, an e n z y m e purif ied f rom Clostridium per#ingens (N-ace ty lneuramin ic acid aldolase; NaNaldolase) ca ta lyzes t he following reversible reac t ion: p y r u v a t e + N-acetyl-Dm a n n o s a m i n e (N-AcMm) ~ N-ace t y l neu rami n i c acid (sialic acid). The recogni t ion of N A c M m as a na tu ra l l y occurr ing suga r leads to t h e ques t ion of t he m e c h...

Since the discovery of the protein product of the ob/ob gene, leptin, knowledge of the neurochemical pathways involved in the regulation of feeding has increased enormously. Our understanding of the mechanisms regulating food intake in man has also progressed greatly over a similar time span. Previous research into the regulation of food intake has largely proceeded through a reductionist appro...

This study was designed to test the hypothesis that long-term hypoxia (LTH) increases fetal plasma leptin and fetal adipose or placental leptin expression and alters hypothalamic and adrenocortical leptin receptor (OB-R) expression. Pregnant ewes were maintained at high altitude (3,820 m) from day 30 to approximately 130 days of gestation. Reduced Po2 was maintained in the laboratory by nitroge...

The aim of this study was to me a su re the op ti cal den sity of four pac ka ble com po si te re sins with widths of 1, 2, 3 and 4 mm, by me ans of Di go ra® (di rect) and Dent Scan Dent Vi ew® (in di rect) di gi tal ima ging systems, in or der to com pa re both methods. Twenty acr ylic pla tes, with the pro po sed thick nes ses, were used, each one con ta i ning a sam ple of each re sin. Each...

Leptin is a circulating hormone secreted by adipose and a few other tissues. The leptin receptor consists of a single transmembrane-spanning polypeptide that is present as a long physiologically important form as well as in several short isoforms. Recent studies have suggested that the anterior pituitary may have a role in the regulatory effects of leptin in animal models. To test this possibil...

Objective(s): The present study aimed to evaluate the receptor of advanced glycation end-products (RAGE), NF-kB, NRF2 gene expression, and RAGE cell distribution in peripheral blood mononuclear cells (PBMC) in subjects with obesity and IR compared with healthy subjects.Materials and Methods: The mRNA expression levels of RAGE, NF-kB, NRF...