BACKGROUND Transverse myelitis has been reported in association with vaccination, including influenza vaccination. OBJECTIVE To describe a case of longitudinally extensive transverse myelitis associated with vaccination with a nasal attenuated novel influenza A(H1N1) vaccine. DESIGN Case report. SETTING Sanford University of South Dakota Hospital. Patient A 27-year-old woman with longitud...

Purpose. To provide an overview of the 2009 H1N1 influenza pandemic and antiviral treatment options for influenza. Summary. Influenza infection causes significant morbidity and mortality every year. The high mutation rate and segmented nature of influenza virus genome gives rise to high genetic variability which enables the virus to escape antiviral and vaccine interventions. A novel H1N1 strai...

OBJECTIVE To describe clinical and epidemiologic features of 2009 novel influenza A(H1N1) in children. DESIGN Analysis of data obtained from standardized report forms and medical records. SETTING Statewide public health surveillance in California. PARTICIPANTS Three hundred forty-five children who were hospitalized with or died of 2009 novel influenza A(H1N1). MAIN EXPOSURE Laboratory-c...

281 The outbreak of the novel H1N1 influenza A, which began in Mexico, has attracted global attention due to the initial high mortality rate and rapid spread since April 2009. Zoonotic infection from pig to human was initially considered as most of the infected cases in Mexico had a history of close contact with pigs. By genotyping and sequencing the causative virus, it was found that the candi...

BACKGROUND In April 2009, an outbreak of novel swine-origin influenza A (2009 H1N1 influenza) occurred at a high school in Queens, New York. We describe the outbreak and characterize the clinical and epidemiologic aspects of this novel virus. METHODS The New York City Department of Health and Mental Hygiene characterized the outbreak through laboratory confirmation of the presence of the 2009...

BACKGROUND The emergence of a novel pandemic human strain of influenza A (H1N1/09) has clearly demonstrated the need for flexible tools enabling the rapid development of new diagnostic methods. METHODS We designed a set of reverse-transcription quantitative real-time PCR (RT-qPCR) assays based on the Universal ProbeLibrary (UPL)--a collection of 165 presynthesized, fluorescence-labeled locked...

OBJECTIVES This report describes the results of an investigation on an outbreak of novel influenza A (H1N1) in an English language Institute in Seoul, Korea in May 2009. METHODS In this outbreak, novel influenza A (H1N1) was confirmed in 22 of 91 trainees, trainers and staff members. The trainees and 2 staff members were isolated in an assigned facility and the rest were isolated in their hom...

Novel influenza A (H1N1) virus infection continues to cause illness and death among persons worldwide. Immunosuppressed patients with influenza virus infection can shed virus for prolonged periods, increasing the chances for development of drug resistance. On August 6, 2009, CDC detected evidence of resistance to the antiviral medication oseltamivir in two severely immunosuppressed patients wit...

This study examined health beliefs associated with novel influenza A (H1N1) immunization among US college undergraduates during the 2009-2010 pandemic. Undergraduates (ages 18-24 years) from a large Midwestern University were invited to complete an online survey during March, 2010, five months after H1N1 vaccines became available. Survey items measured H1N1 vaccine history and H1N1-related atti...

During the spring of 2009, a novel influenza A (H1N1) virus of swine origin caused human infection and acute respiratory illness in Mexico. After initially spreading in North America, the virus spread globally resulting in the first influenza pandemic since 1968. While the majority of illnesses caused by pandemic (H1N1) 2009 were mild and self-limiting, severe complications, including fatalitie...