In late 2012, a novel coronavirus that had not previously been seen in humans was identified for the first time in a resident of the Middle East. The virus, now known as the Middle East respiratory syndrome coronavirus (MERSCoV), 1 has (as of 26 June 2015) caused more than 1350 laboratory-confirmed cases of human infection. Thus far, all patients infected with MERS-CoV have had a direct or indi...

Background: Since April 2012, Middle East Respiratory Syndrome Coronavirus (MERS-CoV) has been confirmed in 8 countries: France, Italy, Jordan, Qatar, Saudi Arabia, Tunisia, United Kingdom (UK) and United Arab Emirates (UAE). Of 55 laboratory-confirmed cases, 31 were fatal for a case fatality rate of 56% (current CDC data June 7, 2013). Although no cases have been reported in the US as of June ...

two male dogs at the age of 3 and 5 months of doberman pinscher and german shepherd breeds were referred to the veterinary hospital of ahvaz university with clinical signs of depression, vomiting, haemorrhagic diarrhoea, profound dehydration, fever and anorexia. the affected dogs had not the history of vaccination. concurrent infection of canine parvovirus and coronavirus was detected in dogs b...

In 2012, a novel coronavirus (CoV) associated with severe respiratory disease, Middle East respiratory syndrome (MERS-CoV; previously known as human coronavirus-Erasmus Medical Center or hCoV-EMC), emerged in the Arabian Peninsula. To date, 114 human cases of MERS-CoV have been reported, with 54 fatalities. Animal models for MERS-CoV infection of humans are needed to elucidate MERS pathogenesis...

The recent discoveries of novel human coronaviruses, including the coronavirus causing SARS, and the previously unrecognized human coronaviruses HCoV-NL63 and HCoV-HKU1, indicate that the family Coronaviridae harbors more members than was previously assumed. All human coronaviruses characterized at present are associated with respiratory illnesses, ranging from mild common colds to more severe ...

We describe the third confirmed case of novel coronavirus infection in a resident of the Arabian Peninsula. Our patient presented, as did 2 prior cases, with severe pneumonia and renal dysfunction requiring intensive care support including assisted ventilation. However, unlike the earlier cases, and despite underlying chronic disease and a single kidney, he survived his infection and has been d...

1Assistant-Director General, Health Security and Environment, World Health Organization, Geneva, Switzerland ([email protected]). In the past four decades, the emergence of new infectious diseases has shaped not only medical concepts, but also those of science and public health; affected political responses at global, regional and national levels; had serious economic impact; and influenced the a...

a 1:1 matched case-control study of calves under 1 month of age was carried out by weekly visits to 7 dairy farms in mashhad from may 2008 to october 2008. fecal samples were collected from a total of 112 calves with clinical signs of diarrhea and from 112 matched animals without clinical signs of diarrhea as assessed by a scoring system. the samples were investigated for the presence of rotavi...

Epidemiology on the ground identifies and tracks a new respiratory virus. L ast year, the infectious disease and public health communities learned of a new severe acute respiratory infection in Saudi Arabia. The stunningly rapid identification of the causative organism, the development of a diagnostic assay, online and ahead-of-print publishing, and heightened global surveillance efforts have m...