The brain rennin-angiotensin system (RAS) has an important role in the regulation of cardiovascular function. The aim of the present study was to determine the effect of reversible inactivation of the central amygdaloid nucleus (Ace) in normotensive rats and rats with renal hypertension (2K-1C). Two groups of normotensive rats were selected for this study. In one group, hypertension was induced...

The brain rennin-angiotensin system (RAS) has an important role in the regulation of cardiovascular function. The aim of the present study was to determine the effect of reversible inactivation of the central amygdaloid nucleus (Ace) in normotensive rats and rats with renal hypertension (2K-1C). Two groups of normotensive rats were selected for this study. In one group, hypertension was induced...

The purpose of this study was to examine pressor hormones and platelet alpha 2-adrenergic receptors in elderly unmedicated free-living subjects. Eighty-seven subjects, 70 +/- 5 years old (mean +/- SD), hypertensive or normotensive (blood pressure less than 160/90 mm Hg) were recruited for measurement of blood levels of norepinephrine, epinephrine, and vasopressin, as well as density and affinit...

Masked hypertension, an elevated daytime ambulatory blood pressure in the presence of a normal office blood pressure, confers an increased cardiovascular risk to adults. We investigated the prevalence, persistence, and clinical significance of masked hypertension in children and adolescents. We enrolled 592 youths (6 to 18 years old). Youths with masked hypertension (n=34) and a random sample o...

Increased cardiac output in pregnancy is associated with cardiac remodeling and possible reduction in contractility, which may worsen in preeclampsia. Left ventricular (LV) geometry and function were compared between nonpregnant controls (n = 12) and normotensive (n = 44) and preeclamptic (n = 15) pregnant women using echocardiography. Load-independent comparisons of LV systolic function compar...

1. The maximal rate of activity of sodium extrusion by the sodium pump, Na+--K+ outward cotransport, passive permeability to sodium and potassium, Na+--Li+ countertransport, and passive permeability to lithium were measured in 45 essential hypertensive patients, 24 young normotensive subjects with at least one hypertensive parent and 24 normotensive subjects with both parents normotensive. 2. T...

Aim: Pulmonary embolism (PE) is the third leading cause of death due to cardiovascular disease. The presence shock or hypotension remains main prognostic clinical marker and date, it only factor that indicates need for aggressive treatment. Most patients with pulmonary are normotensive. Prognostic indicators needed better classify embolism. This study aimed investigate effect lactate level on p...

INTRODUCTION In this study, we investigated the role of exogenous NO donor, sodium nitroprusside (SNP), on hemodynamic responses and survival rate during decompensated hemorrhagic shock in normotensive and hypertensive rat. METHODS Male wistar rats were divided into normotensive and hypertensive groups (n = 12 each). Then, the animals were subjected to decompensated hemorrhagic shock by withd...

1. Responses of adrenomedullin to acute and chronic salt loading were examined in normotensive and hypertensive subjects. 2. In the acute salt load study, isotonic saline (50 ml/kg for 1 h) was intravenously infused into nine normotensive subjects and 11 patients with essential hypertension. Plasma adrenomedullin was higher in hypertensive than in normotensive subjects but was unchanged by sali...