Urea Nitrogen to Creatinine Ratio Related Information: Creatinine, Serum or Plasma Osmolality, Serum Urea Nitrogen, Serum or Plasma Synonyms: BUN to Creatinine Ratio Test includes: Serum creatinine and serum urea nitrogen. Background: Useful to distinguish between preand postrenal diseases, gastrointestinal bleeding, and renal diseases. High BUN/creatinine ratio: Decreased renal perfusion, hypo...

UNLABELLED Tubulointerstitial fibrosis and tubular atrophy play a crucial role in the pathogenesis of chronic kidney disease (CKD). They are also major determinants in chronic kidney disease development and progression in patients with primary renal diseases characterized by persistent or recurrent proteinuria. The purpose of the study was to assess urinary excretion of alpha-glutathione S-tran...

BACKGROUND AND OBJECTIVES Kidney injury molecule-1 (KIM-1) has been suggested as a clinically relevant highly specific biomarker of acute kidney tubular damage. However, community-based data on the association between urinary levels of KIM-1 and the risk for cardiovascular mortality are lacking. This study aimed to investigate the association between urinary KIM-1 and cardiovascular mortality. ...

Hypokalemic periodic paralysis is one of the most distinctive complications of hyperthyroidism and occurs in 8 to 34% of men and 0.2% of women with thyrotoxicosis in Asia. It is also complicated by other diseases with potassium defi ciency such as Bartter’s syndrome, Cushing’s syndrome, and Gitelman’s syndrome. Generally, hypokalemic periodic paralysis with hyperthyroidism is diagnosed by asses...

BACKGROUND Dexmedetomidine, an alpha₂-adrenoceptor agonist, has been evaluated as an adjunct to anesthesia and for the delivery of sedation and perioperative hemodynamic stability. It provokes dose-dependent and centrally-mediated sympatholysis. Coronary artery bypass grafting (CABG) with extracorporeal circulation is a stressful procedure increasing sympathetic nervous system activity which co...

Background: Delayed graft function is a main complication after deceased donor kidney transplantation that adversely affects graft outcome. Difficulties in prediction and early detection of delayed graft function have hindered the ability to perform proper therapeutic interventions. We investigated whether measuring urinary interleukin 18 and neutrophi...

BACKGROUND Acetaminophen overdose may be accompanied by electrolyte disturbances. The basis for electrolyte change appears to be due to increased fractional urinary electrolyte excretion. PURPOSE This study investigated the impact of serum acetaminophen concentration on changes in serum potassium, creatinine and urea concentrations in patients with acetaminophen overdose. METHODS This was a...

in spite of vast improvements in urinary stone treatment (eswl, pnl, ureteroscopy, etc.), metabolic workup concerning the existence of stone forming risk factors are of great importance and can lead to control and even prevention of urinary stone formation in these patients. in this analytical case-control study performed on 266 persons [110 normal persons (56 males and 54 females), 76 patients...

AIMS To determine the prevalence and clinical characteristics of absolute insulin deficiency in long-standing Type 2 diabetes, using a strategy based on home urinary C-peptide creatinine ratio measurement. METHODS We assessed the urinary C-peptide creatinine ratios, from urine samples taken at home 2 h after the largest meal of the day, in 191 insulin-treated subjects with Type 2 diabetes (di...