نتایج جستجو برای: nora efflux pump
تعداد نتایج: 79438 فیلتر نتایج به سال:
NorA is a membrane-associated multidrug efflux protein that can decrease susceptibility to fluoroquinolones in Staphylococcus aureus. We have previously determined that NorA inhibition can increase fluoroquinolone killing activity and post-antibiotic effect. In the current investigation, we studied the killing activity and development of resistance for levofloxacin, ciprofloxacin and norfloxaci...
background: this study aimed to evaluate the role of efflux pump regulator and oxa-23 genes in imipenem resistance acinetobacter baumannii strains isolated from hospitalized patients in tehran, iran. methods: this study was conducted on 60 a. baumannii isolates collected from patients admitted to the shahid motahari and taleghani hospitals in tehran during 2013-14. antibiotic susceptibility tes...
background: shigella spp. are gram negative bacteria, which are of global public health importance. the growing of multidrug-resistant shigella isolates are a major problemaround the world. methods: overall, 50 isolates of shigella spp. from children diarrheic stools were studied. the isolates were identified and confirmed using biochemical, serological and molecular methods (ipah, wbgz and rfc...
conclusion these data show that the identified gene encoded tet resistance gene as mfs–type multi-substrate efflux transporter, which contributes to intrinsic resistance on range of structurally unrelated compounds in salmonella species. background tetracyclines (tcs) are a type of broad-spectrum bacteriostatic antibiotics used for treatment of a wide variety of infections. these antibiotics ev...
conclusions this study represented an increasing rate of mdr p. aeruginosa in burn and wound samples. efflux mexab genes were detected in all mdr and pdr strains. the p. aeruginosa strain isolated from burn cases showed higher drug resistance and pdr resistance was only noted in a burn sample. materials and methods one-hundred and fifty p. aeruginosa were isolated from burn and wound infections...
Background and Aims: Pseudomonas aeruginosa is one of the most important pathogens of nosocomial infections, especially in the ICU (Intensive Care Unit), which has resistance to a wide range of antibiotics, especially Carbapenems. Among the most important resistance mechanisms of this bacteria against carbapenems are MexAB-OprM efflux pump. Therefore, the aim of this study was to evaluate the g...
Background and Objective: Efflux pumps are one of the major resistance mechanisms in Pseudomonas aeruginosa that inhibit the accumulation of antibiotics in bacterial cells. The aim of this study was determining the effect of carbonyl cyanide 3-chlorophenyl hydrazone (CCCP) and detecting the overexpression of pump MexCD-oprJ in P. aeruginosa isolated from burn patients in Shahid Motahari hospita...
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