Two adult male baboons (Papio cynocephalus) were infected by urethral catheter with a Type D strain of Chlamydia trachomatis isolated from a male patient with nongonococcal urethritis. Chlamydial organisms were shed from the urethra for about 90 days and serum antibody developed. Intraurethral re-inoculation of homologous and heterologous (Type I) strains of Chalmydia, 4 and 11 months later, re...

Sir, Chlamydia trachomatis and Neisseria gonorrhea are the leading reportable causes for sexually transmitted diseases (STDs) in the United States.[1,2] In UK, gonorrheal disease is considered the second most common sexually transmitted infection of bacterial origin.[3] In France, the average number of Neisseria gonorrhea isolated per laboratory per year decreased from 10.6 in 1986 to 0.6 in 19...

Prostatitis is usually more common after nongonococcal urethritis (NGU) than after gonococcal urethritis (King, 1964; British Medical3Journal, 1972; Schofield, 1972). Observations made during the early part of a tour of duty in 1970 as Venereologist at the British Military Hospital in Singapore suggested that the reverse might be the case there. It was, therefore, decided to examine the prostat...

Chlamydia trachomatis has been recognized as a pathogen of trachoma, nongonococcal urethritis, salpingitis, endocervicitis, pelvic inflammatory disease, inclusion conjunctivitis of neonates, follicular conjunctivitis of adults, infantile pneumonia and associated conditions. Chlamydial infections during pregnancy may also cause a variety of perinatal complications. Different antigenic strains of...

The limulus assay for the detection of bacterial endotoxin has been applied to the study of synovial fluid. Three of 5 patients (60%) with culture-positive gonococcal arthritis had positive SF limulus assay results; as did 2 of 11 (18%) with presumptive evidence of gonococcal arthritis, 3 of 6 (50%) with nongonococcal infectious arthritis, and none of 47 patients with noninfectious arthritis. E...

The occurrence of Staphylococcus saprophyticus, Chlamydia trachomatis, and Neisseria gonorrhoeae in urethral specimens of 252 men attending a venereal disease clinic was studied. When using a selective broth medium containing novobiocin and nalidixic acid, Staph. saprophyticus was isolated from 20.8% of 178 men with symptoms of urethritis and from 14.9% of 74 men without such symptoms. Staph. s...