OBJECTIVES This study aims to summarise the evidence on more than 140 pharmacological and non-pharmacological treatment options for major depressive disorder (MDD) and to evaluate the confidence that patients and clinicians can have in the underlying science about their effects. DESIGN This is a review of systematic reviews. DATA SOURCES This study used MEDLINE, Embase, Cochrane Library, Ps...

Introduction: MCI is considered as a prodromal stage between normal cognitive aging and dementia given its potential to develop into various forms of dementia, most notably Alzheimer’s disease (AD). This translates need for effective pharmacological non-pharmacological treatments prevent the progression subsequently slowing AD onset. review aims discuss effectiveness interventions in progressio...

Currently, a pharmacological disease-modifying treatment for dementia is not available, but different non-pharmacological approaches appear to be useful. In this chapter, we describe traditional treatments such as cognitive and emotion-oriented interventions, sensory and multi-sensory stimulation interventions and also potential‐ ly alternative interesting options such as behavioural therapy, a...