Background:  Natural Killer cells express killer inhibitory receptors specific for HLA-class I molecules.  These receptors could induce signals that determine NK cells ability to mediate cytotoxicity.  Purified soluble form of HLA class I molecules (sHLA) could bind to NK cell receptors and down-regulate the NK killer function. Objective:  To evaluate the influence of sHLA and two monoclonal an...

background: natural killer (nk) cells play an important role in early stages of innate immune responses against viral and tumoral attacks. activation of nk cells by leishmaniasis results in secretion of cytokines such as interferon (ifn)-γ and tumor necrosis factor (tnf)-α, which enhances the phagocytosis and clear­ance of parasite. lipophosphoglycan 3 (lpg3), the leishmania homologous with grp...

This paper presents distributed embedded monitoring system that is developed for small aircrafts, sports and ultralights airplanes. System is made from modules connected by industrial bus CAN. This low cost system is trying to solve bad situation with many ultralights without any digital measurement unit due to their prices. The contribution shows basic architecture of the embedded monitoring s...

LTC Rich Melnyk is an Army Aviator and Assistant Professor in the Department of Civil and Mechanical Engineering at the United States Military Academy, West Point. He developed and implemented the first course offering of Thermal-Fluid Systems I in 2005. He was an Instructor and Assistant Professor from 2004-2007 and returned to teaching in 2015. He has a PhD in Aerospace Engineering, a PE in M...

Natural killer (NK) cells are a subset of lymphocytes which play a crucial role in early innate immune response against infection and tumor transformation. Furthermore, they secrete interferon-γ (IFN-γ) and tumor necrosis factor (TNF) prompting adaptive immu-nity. NK cells distinguish the unhealthy cells from the healthy ones through an array of cell-surface receptors. Human NK cells use inhibi...