The carcinogenicity and mutagenicity of chemicals may be modulated by other chemicals, including those prepared by organic synthesis. Considering the several drawbacks of synthetic compounds vis-a-vis the human organism, the lignin biomass component was examined for this purpose. The binding affinity of lignin samples prepared by chemical and biological modification of lignin products derived f...

Abstract:N-nitrosaminesis a kind of poison which can induce cancer. Nitrite can react withsecondary amines to form N-nitrosamines in meat production. The objective of this experiment was to study N-nitrosamines formation ofthree kinds offermentationcelery powder (FCP506, FCP504, and FCP-homemade) and nitritein vitro nitrosation reaction system bydifferent pH, temperature, and the ratio of the s...

A rabbit cytochrome P-450llE2 full-length cDNA was cloned into a yeast episomal plasmid (YEp13) between the copper-responsive yeast metallothionein gene promoter (CUP7) and the iso-I-cytochrome c gene terminator (CYCI), and the cytochrome P-450 was expressed in Saccharomyces cerevisiae. The microsomal fraction prepared from copper-treated cells exhibited a ferrous carbonyl difference spectrum w...

N -nitrosamines are contaminants of emerging concern, and controlling these chemicals in potable water recycled for reuse has become important protecting public health. This study aimed to evaluate the influence alkyl chain lengths -nitrosamine precursors (secondary tertiary amines) on formation via chloramination. The molar conversion efficiency from dimethylamine, an -nitrosodimethylamine (ND...

Chemically induced tumors in mice provide a system to investigate tumor-associated antigens (TAA). The cell surface glycoprotein antigens on such tumor cells have been identified as suitable targets for immune attack. The induction of immune responses against (TAA) in N-nitrosodiethylamine (DEN) exposed mice has been examined. In order to present antigens to the immune system, the liposome was ...