Minoxidil (Mx), a pyrimidine N-oxide, is used therapeutically as an antihypertensive agent and to induce hair growth in patients with male pattern baldness. Mx NO-sulphate has been implicated as the agent active in producing these effects. This paper describes the purification of a unique sulphotransferase (ST) from rat liver cytosol that is capable of catalysing the sulphation of Mx. By using ...

Methyl parathion (MP) is an organophosphate pesticide illegally applied to the interiors of many hundreds of homes throughout the United States by unlicensed pesticide applicators. Public health authorities developed a protocol for investigating contaminated homes and classifying their need for public health interventions. This protocol included environmental screening for MP contamination and ...

Phosphatase enzymes regulate organic phosphorus (P) turnover in soil, but a clear understanding remains elusive. To investigate this, phosphomonoesterase and phosphodiesterase activities were determined by using para-nitrophenol (pNP) analogue substrates in a range of temperate pasture soils from England and Wales. Substrate-induced phosphatase activity ranged between 2.62 and 12.19 micromol pN...

In 1994 officials from the Ohio Department of Health reported that some residents of Lorain County, Ohio, possibly had been exposed to methyl parathion (MP), a highly toxic restricted-use pesticide. The U.S. Centers for Disease Control and Prevention (CDC) assisted in the investigation by providing epidemiologic and laboratory support to the state and local health departments. Although the init...

An efficient, green and reusable catalyst for organic pollutant wastewater treatment has been a subject of intense research in recent decades due to the limitation current technologies. Cellulose based aerogel composites are considered be an especially promising candidate next-generation catalytic material. This project was conducted order evaluate behavior ability sugarcane bagasse aerogels re...

Secondary effluent reclamation and reuse is an effective solution to the water shortage problem, safety of reused a matter increasing concern. p-Nitrophenol (PNP), common secondary pollutant, can be efficiently removed using eco-friendly bioaugmented soil aquifer treatment (SAT) system at laboratory scale. In this study, sewage plant in Changchun was selected as case study apply SAT for field s...

Hybridisation of mesoporous organosilicas (MO) to reinforce the surface capability in adsorption and stabilisation noble metal nanoparticles is great attention generating/supporting within their matrices transforming them into efficient heterogeneous catalysts. Here, we used a unique hybrid organic-inorganic silica which pore profile pattern was similar well-known silica, SBA-15 for catalysis. ...

A thermophilic and actinic bacterium strain, MH-1, which produced three different endochitinases in its culture fluid was isolated from chitin-containing compost. The microorganism did not grow in any of the usual media for actinomyces but only in colloidal chitin supplemented with yeast extract and (2, 6-O-dimethyl)-beta-cyclodextrin. Compost extract enhanced its growth. In spite of the format...

Glucuronidation of iodothyronines in rat liver is catalyzed by at least three UDP-glucuronyltransferases (UGTs): bilirubin UGT, phenol UGT, and androsterone UGT. Bilirubin and phenol UGT activities are regulated by thyroid hormone, but the effect of thyroid status on hepatic glucuronidation of iodothyronines is unknown. We examined the effects of hypothyroidism induced by treatment of rats with...