BACKGROUND Skin flap necrosis is a common complication after mastectomy and breast reconstruction. It has been proven that nitroglycerin ointment, as a topical vasodilator, can decrease the rate of skin flap necrosis after mastectomy and breast reconstruction. However, nitroglycerin can cause several side effects, including headache, dizziness, and hypotension. The purpose of this study was to ...

background  : on-pump coronary artery bypass graft (cabg) surgery impairs gas exchange in the early postoperative period. the main object on this study was evaluation of changes in arterial blood gas values in patients underwent on pump cabg surgery receiving different dose of intravenous nitroglycerin (ntg). methods : sixty-seven consecutive patients undergoing elective on-pump cabg randomly e...

sublingual nitroglycerin (tng) has been introduced as a promising provocative agent for tilt table testing, but it has not been compared directly with the standard isoproterenol (iso) infusion test previously. we tried to assess the diagnostic value and safety of tng tilt testing as compared with iso infusion in patients with unexplained syncope. tng and iso tilt tests were performed in two suc...

The aim of this study was to assess whether intraoperative transesophageal echocardiography with nitroglycerin infusion could identify viable myocardium. Twenty-eight patients with coronary artery disease with regional dysfunction underwent transesophageal echocardiography during bypass surgery. A transgastric left ventricular cross-sectional image at the midpapillary level was obtained and div...

Nitroglycerin acts, in part, to reduce arterial impedance, and thus left ventricular work. The reduction in arterial impedance is largely attributable to a fall in systemic vascular resistance, but may also be due to an increased distensibility of the arterial tree. In this study, volume distensibility of forearm arteries was calculated from measurements of pulse-wave velocity before and during...

conclusions the evidence that btx-a decreases ntg-induced cgrp-li and sp-li levels in trigeminovascular system suggests that btx-a attenuates migraine by suppression of neuropeptide release. btx-a injections for migraine at acupoint-sites and fixed-sites are effective. acupoint-sites btx-a administration shows more efficacy for migraine than fixed-sites application. results local btx-a injectio...

OBJECTIVE As an important prognostic factor of coronary artery bypass grafting (CABG), graft vasospasm can be observed in all currently used graft conduits. Radial artery (RA) vasospasm is more prone to occur in comparisons with internal mammary artery (IMA) and great saphenous vein (GSV). There is still controversy about which antispasmodic agent is superior to different grafts, especially to ...

BACKGROUND Nitroglycerin is effective in relieving myocardial ischemia; however, intracoronary nitroglycerin often fails to relieve angina and has been reported to have deleterious effects on subendocardial blood flow. To understand the mechanisms involved, we evaluated the direct effect of nitroglycerin on coronary circulation of the ischemic hearts. METHODS AND RESULTS We measured the phasi...

Coronary artery disease patients frequently have left ventricular wall motion abnormalities. Though nitroglycerin is commonly used in ischemic heart disease, its effects on wall motion abnormalities is unknown. In this study we have evaluated the effects of nitroglycerin on wall motion abnormalities and on ejection fraction in 25 patients. Sixteen had coronary artery disease (greater than 70% l...

We used a combination of transcranial Doppler ultrasonography and single-photon emission computed tomography to noninvasively assess changes in the diameter of the middle cerebral artery induced by sublingual nitroglycerin in 10 healthy subjects. Nitroglycerin reduced mean blood flow velocities without concurrently changing regional cerebral blood flow in the perfusion territory of this vessel....