نتایج جستجو برای: niosomal
تعداد نتایج: 214 فیلتر نتایج به سال:
Abstract Bacterial conjunctivitis characterized as pink eye referred as an inflammation of an eye caused by the enlargement of blood vessels present in conjunctiva, resulting in a red or bloodshot appearance of the eyes. Topical ocular delivery is found to be useful in treating conjunctivitis, but to maintain an effective drug concentration at a site of action in order to achieve desired pha...
Niosomes have potential applications in topical drug delivery system. play an increasingly important role as they can reduce toxicity and modify pharmacokinetic bio-availability. Topically applied niosomes increase the residence time of drugs stratum corneum epidermis, while reducing systemic absorption drug. It act containing reservoirs modification vesicular compositions or surface properties...
Abstract Purposes Calcium channel blockers, such as diltiazem (DLZ), are important drugs for wound repair treatment. This current study used an ultrasonic method to increase the cutaneous delivery of (DLZ) niosomes. Methods The impact cholesterol:surfactant ratio on DLZ-loaded niosome formulations was investigated. Differential scanning calorimetry (DSC), powder X-ray diffraction (PXRD), electr...
Aim and Background: Vincristine is a herbal anticancer drug which is used to treat a wide range of cancers such as lymphoma. Niosomes are important drug carriers. The aim of this study was to prepare PEGylated niosomal form of vincristine in order to increase its efficacy in lymph nodes’ cancer. Material and Methods: PEGylated niosomal vincristine (PEG-nVCR) was prepared by thin film hydrat...
Background & Aim: Silibinin is a blend of flavonoids, which is extracted from Marianum Silybum, and its anti-cancer effects on breast cells have been studied. The aim of this study was to provide physiochemical evaluation of various formulations of the niosomal system containing silibinin, in order to achieve targeted formulation to better fight breast cancer cells. Methods: Nano-carriers were...
Background Despite current therapies, lung cancer remains a global issue and requires the creation of novel treatment methods. Recent research has shown that biguanides such as metformin (MET) silibinin (SIL) have potential anticancer effect. As consequence, effectiveness MET SIL in combination against cells was investigated this study to develop an effective method. Methods Niosomal nanopartic...
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