نتایج جستجو برای: nicotineamide phosphoribosyltransferase
تعداد نتایج: 2198 فیلتر نتایج به سال:
The enzymic capacities of the de novo and the salvage pathways for purine nucleotide synthesis were compared in rat in normal, differentiating, and regenerating liver, and in three hepatomas of widely different growth rates. The activities of the key de novo and salvage enzymes were also determined in mouse lung and Lewis lung carcinoma, in human kidney and liver, and in renal cell carcinoma an...
Highly purified preparations of iV-l-(S’-phosphoribosyl)adenosine triphosphate:pyrophosphate phosphoribosyltransferase from Salmonella fyphimurium have been obtained. The phosphoribosyltransferase is the first enzyme unique to histidine biosynthesis and is sensitive to feedback inhibition by histidine. The procedure used for purification preserved the histidine sensitivity of the enzyme. A mole...
This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi: 10.1111/pcmr.12037 © 2012 John Wiley & Sons A/S Nicotinamide phosphoribosyltransferase (NAMPT) is over-expressed in ...
A B S T R A C T We have previously described a 14-yrold boy with hyperuricemia, renal failure, and accelerated purine production resistant in vivo and in vitro to purine analogs. This patient demonstrated normal red cell hypoxanthine-guanine phosphoribosyltransferase (HPRT) heat stability, electrophoresis at high pH, and activity at standard substrate levels. In the present report an abnormal H...
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