Abstract Background Evans’ syndrome (ES) is a rare and chronic autoimmune disease characterized by the concomitant or sequential association of auto-immune hemolytic anemia (AIHA) with immune thrombocytopenia (ITP), less frequently neutropenia positive direct anti-human globulin test. ES represents up to 7% AIHA around 2% ITP. Studies have found that coronavirus 2019 (COVID-19) may be associate...

Autoimmune haemolytic anaemia (AIHA) in mantle cell lymphoma (MCL) is a rare but life-threatening complication. To date, there are no relevant data for treatment of AIHA in MCL. Ibrutinib, which has been approved for relapse/refractory MCL, is an immunomodulatory drug inhibiting Th2 activation and consequently the production of autoantibodies. We report a case of MCL with AIHA in which this for...

Spherocytic red cells with reduced membrane surface area are a feature of hereditary spherocytosis (HS) and some forms of autoimmune hemolytic anemia (AIHA). It is generally assumed that membrane loss in spherocytic red cells occurs during their sojourn in circulation. The structural basis for membrane loss in HS is improper assembly of membrane proteins, whereas in AIHA it is due to partial ph...

to study the effect of different weed control methods in tomato, an experiment was conducted as completely randomized block design with three replications at the research farm of university of tehran (karaj) in 2008. the treatments consisted of post emergence (at recommended rate) or pre emergence (reduced rate in combination with mulch) application of metribuzin, rimsulfuron and sulfosulfuron,...

Abstract Downy brome ( Bromus tectorum L.) is a highly invasive winter annual grass that can fill open niches in native plant communities. Prescribed burning often used to control B. and be combined with herbicide treatments extend the duration of promote community. Several herbicides have been evaluated conjunction for control, although indaziflam has not. In September 2017, two –infested site...

Autoimmune haemolytic anaemia (AIHA) is a rare (prevalence 0.2 -1.0 per 100,000 population) but a potentially fatal condition. Diagnosis of AIHA is based mainly on Direct Agglutination Test (DAT/Coomb's test). AIHA is classified into warm (optimal autoantibody reactivity at 37°C) and cold (optimal autoantibody reactivity at 4°C) types. Based on the presence or absence of an underlying cause, it...

CD47 deficiency results in lethal autoimmune haemolytic anaemia (AIHA) and mild spontaneous thrombocytopenia in non-obese diabetic mice. It is unknown whether CD47 has an impact on AIHA of the warm type or autoimmune thrombocytopenia (ITP) in humans. Healthy blood donors (n= 11), patients with AIHA (n= 13), patients with ITP (n= 18) and one patient with Rh(null) phenotype were investigated. CD4...

OBJECTIVE To present and discuss the treatment of autoimmune hemolytic anemia (AIHA). METHODS The medical records of all patients (n=19) diagnosed in a tertiary hematology center between 1999 and 2010 were retrospectively reviewed. RESULTS Median age at diagnosis of AIHA was 5 years (range: 4 months-17 years). In all, 13 patients had primary (idiopathic) AIHA, whereas 2 had primary Evans Sy...

Autoimmune haemolytic anaemia (AIHA) is known to be associated with Hodgkin's disease (HD) but is uncommon. It usually presents at the time of initial diagnosis of HD or during the course of the disease but AIHA preceding the diagnosis of HD is very rare. We describe here 2 cases of AIHA who presented one year before the diagnosis of HD. There was no evidence of a coexisting disease at initial ...

Coombs' negative autoimmune hemolytic anemia (AIHA) is a rare disease which shares similar clinical and hematological features with Coombs' positive AIHA, but its exact frequency remains unknown. There have been few reports of idiopathic thrombocytopenic purpura (ITP) and Coombs' negative AIHA associated with other lymphoproliferative disorders (LPDs). Since there is a well known association be...