The National Formulary of India (NFI), 4th edition, 2010 (pre-print version) was published amidst a lot of advance publicity by the Indian Pharmacopoeia Commission (IPC). The book was released by Shri K. Chandramouli, Secretary, Ministry of Health and Family Welfare, Govt. of India and Chairman, IPC on 16th December 2010, at Nirman Bhawan, New Delhi, in the presence of offi cials.[1] Coming aft...

Background: Nuclear factor I-A (NFI-A), a phylogenetically conserved transcription/replication protein, plays a crucial role in mouse brain development. Previous studies have shown that disruption of the Nfia gene in mice leads to perinatal lethality, corpus callosum agenesis, and hydrocephalus. Results: To identify potential NFI-A target genes involved in the observed tissue malformations, we ...

We report on a genome-wide association study (GWAS) from the CRC for Beef Genetic Technologies using the 50k Illumina SNP chip. Here, we present the results for net feed intake (NFI), body weight and hip height. The aims of this analysis are to discover SNPs associated with all traits but especially NFI and to test the consistency of SNP effects across datasets and breed types using the weight ...

A central question is how various stages of neuronal development are integrated as a differentiation program. Here we show that the nuclear factor I (NFI) family of transcriptional regulators is expressed and functions throughout the postmitotic development of cerebellar granule neurons (CGNs). Expression of an NFI dominant repressor in CGN cultures blocked axon outgrowth and dendrite formation...

OBJECTIVE Rapid and simple tests for diagnosing nerve function impairment (NFI) in leprosy are required in integrated settings. We examined whether simplified tests performed by newly trained general health workers (GHWs) have comparable diagnostic accuracy to the reference test conducted by experienced physiotherapists. DESIGN This multi-centre study from India and Bangladesh evaluated three...

Chicken TGGCA proteins belong to the ubiquitous, eukaryotic family of NFI-like nuclear proteins, which share an identical DNA binding specificity. They are involved in viral and cellular aspects of transcriptional regulation and they are capable of stimulating Adenovirus initiation of replication. Using microsequencing data from peptides of isolated proteins and PCR supported cloning, we have d...

BACKGROUND The aim of this study was to evaluate the sensitivity, specificity, and likelihood ratio of standard diagnostic parameters C/D, NFI, and MD and their applicability in diagnostics of primary open-angle glaucoma. MATERIAL AND METHODS This study included 194 subjects (371 eyes), ages 30 to 65 years old, who underwent full ophthalmologic examination and HRT, GDx, and FDT examinations. ...

The elucidation of the transcriptional mechanisms that regulate glial fibrillary acidic protein (GFAP) gene expression is important for the understanding of the molecular mechanisms that control astrocyte differentiation during brain development. We investigated regulatory elements located in a proximal region of the GFAP promoter, important for expression in cortical precursor cells differenti...

PURPOSE Damage to the corneal epithelium results in the massive secretion of fibronectin (FN) shortly after injury and induces the expression of its integrin receptor alpha5beta1. The authors reported previously that FN induces alpha5 expression in human corneal epithelial cells and rabbit corneal epithelial cells by altering the binding of the transcription factor (TF) Sp1 to a regulatory elem...