نتایج جستجو برای: neuroprotective agents

تعداد نتایج: 375266  

Journal: :Investigative ophthalmology & visual science 2011
Natalie D Bull Thomas V Johnson Guncha Welsapar Nicholas W DeKorver Stanislav I Tomarev Keith R Martin

PURPOSE. To validate an established adult organotypic retinal explant culture system for use as an efficient medium-throughput screening tool to investigate novel retinal ganglion cell (RGC) neuroprotective therapies. METHODS. Optimal culture conditions for detecting RGC neuroprotection in rat retinal explants were identified. Retinal explants were treated with various recognized, or purported,...

Journal: :GSC biological and pharmaceutical sciences 2021

Neuroprotection is the preservation of structure and function neurons from insults cellular injuries caused by a variety agents or neurodegenerative diseases. Medicinal plants possess neuroprotective effects via mechanisms that include inhibiting protein-based deposit accumulation, oxidative stress, neuroinflammation, correcting defects neurotransmitters such as acetylcholine dopamine [1-3]. Th...

Journal: :Expert opinion on investigational drugs 2012
Petra Dunkel Christina Ll Chai Beáta Sperlágh Paul B Huleatt Péter Mátyus

INTRODUCTION According to the definition of the Committee to Identify Neuroprotective Agents in Parkinson's Disease (CINAPS), "neuroprotection would be any intervention that favourably influences the disease process or underlying pathogenesis to produce enduring benefits for patients" [Meissner W, et al. Trends Pharmacol Sci 2004;25:249-253]. Preferably, neuroprotective agents should be used be...

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