A recent study of dopaminergic neurons in the brain of larval zebrafish has important implications for interpreting the natural actions of neuromodulators in the spinal cord.

A recent study in the locust olfactory system shows how neuromodulators can alter the rules of synaptic plasticity to form associative memories through the use of 'tagged' synapses.

Membrane receptors for neuromodulators (NM) are highly regulated in their distribution and efficacy-a phenomenon which influences the individual cell's response to central signals of NM release. Even though NM receptor regulation is implicated in the pharmacological action of many drugs, and is also known to be influenced by various environmental factors, its functional consequences and modes o...

The superior colliculus is part of a broader neural network that can decode whisker movements in air and on objects, which is a strategy used by behaving rats to sense the environment. The intermediate layers of the superior colliculus receive whisker-related excitatory afferents from the trigeminal complex and barrel cortex, inhibitory afferents from extrinsic and intrinsic sources, and neurom...

To survive and successfully reproduce animals need to maintain a balanced intake of nutrients and energy. The nervous system of insects has evolved multiple mechanisms to regulate feeding behavior. When animals are faced with the choice to feed, several decisions must be made: whether or not to eat, how much to eat, what to eat, and when to eat. Using Drosophila melanogaster substantial progres...