In order to elucidate the relationships between hierarchical structures within the neocortical neur carried by an ensemble of neurons encompassing a single voxel, it is essential to predict through vo LFPs representing average extracellular potentials, which are expressed in terms of interstitial po in networks of gap-junctionally connected astrocytes and synaptically connected neurons. These p...

We st udy th e sequences generated by neuronal recurrence equat ions of th e form X n = l [~l then there is a neuronal recurrence equat ion with memory length kr that generates a sequence of period lcmlp «,...

BACKGROUND The Notch signaling pathway is an evolutionarily conserved intercellular signaling module essential for cell fate specification that requires endocytosis of Notch ligands. Structurally distinct E3 ubiquitin ligases, Neuralized (Neur) and Mind bomb (Mib), cooperatively regulate the endocytosis of Notch ligands in Drosophila. However, the respective roles of the mammalian E3 ubiquitin ...

A method for red ucing t he number of uni ts in t he hidden layers of a feed-for war d neur al network is pr esented . Starting wit h a net that is oversize, t he redundan t unit s in t he hidden layer are elimina ted by introducing an addit ional cost fun ct ion on a set of auxiliary linear response uni ts . T he extra cost funct ion enables t he auxiliary units to fuse together the redundant ...

In the present work we consider the mathematical model that describes brain tumour growth (glioblastomas) under medical treatment. Based on the medical study presented by R. Stupp et al. (New Engl Journal of Med 352: 987996, 2005) which evidence that, combined therapies such as, radiotherapy and chemotherapy, produces negative tumour-growth, and using the mathematical model of P. K. Burgess et ...

where irregular and bizarre ganglionic masses exist in the complete absence of myotomes. The reduction in the number of ganglia and spinal nerves following somite removal, and especially an increase following the interpolation of an additional somite, constitute strong experimental support of Lehmann's view that the normal segmentation of spinal ganglia and nerves is determined by the mesoderma...

Feedforward neural networks have been successfully applied to a variety of classification problems, but th e number of classes used for experiments was too small to app ly the results directly to large-scale problems. This pap er presents several st rategies for applying feedforward neur al networks to large-scale, complex classificat ion problems: a two-stage classification scheme, a rapid lea...