Background and Objectives: Diabetes, a common metabolic disorder, is prevalent in many countries. Nephropathy is a main debate’s side effect. Role of oxidative stress is well known in induction of diabetic nephropathy while carvacrol is a potent anti-oxidant that might attenuate oxidative stress. The aim of this study was to explore the effect of carvacrol in d...

Prolonged duration of diabetes mellitus, poor long term glycemic control and raised blood pressure have all been clearly related to the development of diabetic nephropathy. Evidence exists to suggest that a subset of individuals with diabetes have a genetic predisposition to diabetic nephropathy. Cases of diabetic nephropathy cluster in families and a parental history of hypertension is more co...

the effect and outcome of pregnancy in patients with chronic idiopathic glomerulonephritis was studied. the study population consisted of 98 patients. all patients were divided into 8 groups according to presence, absence or coexistence of 3 general risk factors such as hypertension, renal failure and nephrotic syndrome. the adverse effect of renal disease and risk factors on the outcome of pre...

Background and Aim: Diabetic nephropathy is the most common cause of end-stage renal disease albuminuria earliest manifestation diabetic nephropathy.Oxidative stress inflammation caused by advanced glyco-oxidation end products contribute to micro macrovascular complications diabetes. Monocyte high-density lipoprotein (HDL) cholesterol ratio (MHR) an essential indicator oxidative stress. In this...

Chronic kidney disease (CKD) is a worldwide public health problem that affects millions of people from all racial and ethnic groups. At end of 2013, over 300,000 Japanese patients had maintenance dialysis therapy (JSDT). In Japan, the major causes of end stage kidney disease (ESKD) are chronic glomerulonephritis (particularly IgA nephropathy), type 2 diabetic nephropathy, and hypertensive nephr...

BACKGROUND Diabetic nephropathy is a major complication of diabetes and an established risk factor for cardiovascular events. Lipid abnormalities occur in patients with diabetic nephropathy, which further increase their risk for cardiovascular events. We compared the degree of dyslipidemia among type 2 diabetes mellitus (T2DM) subjects with and without nephropathy and analyzed the factors assoc...

BACKGROUND AND OBJECTIVES This study examined age-specific incidence and prevalence of renal replacement therapy attributed to analgesic nephropathy from 1971 through 2005 and adjusted comorbidity prevalence and survival of patients who had analgesic nephropathy and were on renal replacement therapy (compared with control subjects without diabetes). DESIGN, SETTING, PARTICIPANTS, & MEASUREMEN...