OBJECTIVES To investigate the incidence, causes, predictors, and outcomes of septicemia in the first week of life in a national cohort of extremely premature infants. METHODS A prospective study of survival of all infants with gestational age of <28 weeks or birth weight of <1000 g who were born in Norway in 1999-2000 was performed. Data on the maternal prenatal history, delivery, and neonata...

Objective: To study the maternal risk factors and clinico-bacteriological profile of early onset sepsis (EOS) and performance of sepsis screen parameter in a tertiary care neonatal unit. Methods: Relevant data of neonates born during the study period were obtained from their case records. A diagnosis of early onset sepsis was made if either clinical sepsis developed within 48 hours of life and ...

We conducted a case matched control study to observe the adverse effects of ciprofloxacin used in neonatal septicemia We enrolled 30 neonates with multidrug-resistant septicemia who were treated with intravenous ciprofloxacin for 14 days. Thirty matched neonates with septicemia treated with other antibiotics were enrolled as controls There was no difference in the mean serum electrolytes, hepat...

OBJECTIVE Bacterial sepsis continues to be a major cause of morbidity and mortality in newborns. Bacterial pathogens of neonatal septicemia may vary from one country to another and within a country from one hospital or region to another. Both gram-negative and gram-positive bacteria are responsible in neonatal sepsis. This study was undertaken to determine the prevalent bacterial agents of neon...

Background: Neonatal infections currently cause 1.6 million deaths in developing countries. Resistance to commonly used drug is emerging as the most important problem globally. Therefore rational use of antibiotic is a priority to reduce the burden of treatment failure. Objective: To evaluate the magnitude of neonatal infections in the neonatal ward of a medical institution and pattern of antib...