Ubiquicidin (UBI) [29-41] is a synthetic cationic antimicrobial peptide that preferentially binds to bacterial cell membrane at the site of infection. We aimed to assess diagnostic value of 99mTc-UBI [29-41] as a radiopharmaceutical in differentiation of bacterial infection from sterile inflammation in suspected orthopedic implants. Nine patients suspected for orthopedic implant infection, all ...

BACKGROUND AND OBJECTIVES The objective of this study was to evaluate the risk of Gram-negative bacterial infections in febrile neutropenic patients and to develop a specific risk score. DESIGN AND METHODS This prospective study included 513 consecutive febrile neutropenic, evaluable patients. Forty-five per cent of the patients were receiving prophylactic gut decontamination, and 6% were rec...

OBJECTIVE This study was undertaken to evaluate the discriminatory power of the peripheral white blood cell (WBC) count to identify bacterial infections in a cohort of febrile neonates (<or=28 days of age) presenting to an emergency department. METHODS Retrospective medical record review using descriptive statistics and a receiver operating characteristic (ROC) curve. Neonates who presented t...

Patients with cancer are at high risk for infections caused by antibiotic resistant gram-negative bacteria. In this review, we summarize trends among the major pathogens and clinical syndromes associated with antibiotic resistant gram-negative bacterial infection in patients with malignancy, with special attention to carbapenem and expanded-spectrum β-lactam resistance in Escherichia coli, Kleb...

BACKGROUND & OBJECTIVES Early identification of bacterial infection in patients with fever is important for prompt treatment. However, the available parameters such as C-reactive protein (CRP) and leukocyte counts are not very specific. This study was aimed to assess the diagnostic value of procalcitonin (PCT), CRP, interleukin-6 (IL-6) and serum amyloid A (SAA) for bacterial infection in febri...

Background & Aim:Vaginal disease has always been a great concern of women. Medicinal plants as natural resources with fewer side effects can effectively treat these infections given the diversity of these infections, resistance to antibiotics and side effects of existing drugs. The present study aimed to compare antimicrobial effects of methanol extract of Francoeuria Undul...

background and objectives: coagulase negative staphylococcus (cons) is frequently isolated from blood cultures but their significance is difficult to interpret. cons bacteria which are often previously dismissed as culture contaminants are attracting greater importance as true pathogens in the past decades. clinical evaluation of these isolates suggests that although there is a relative increas...

background: the role of the hospital environment as a source of dissemination of pathogens is critical. environmental surfaces in the intensive care units (icus) are suitable for the growth of gram-negative bacteria that normally circulate between the environment and patients and can cause outbreaks of nosocomial infections. in this study, the prevalence of gram-negative bacilli in the environm...