OBJECTIVE Early operative debridement is a major determinant of outcome in necrotizing fasciitis. However, early recognition is difficult clinically. We aimed to develop a novel diagnostic scoring system for distinguishing necrotizing fasciitis from other soft tissue infections based on laboratory tests routinely performed for the evaluation of severe soft tissue infections: the Laboratory Risk...

Necrotizing gingival disorders are rare conditions of the gingival tissues. Patients typically present with severe discomfort, halitosis, bleeding, and ulcerated oral tissues. This condition will typically present in patients who are under psychological stress, malnourished, and/or who are immunosuppressed. This case report will present a patient with acute ulcerative necrotizing gingivitis (AN...

INTRODUCTION Necrotizing sialometaplasia is a rare disease first described in 1973. It involves salivary gland in the oral cavity. CASE PRESENTATION We present a 32-year-old, white, male with rare bilateral localization of necrotizing sialometaplasia. CONCLUSION Clinically and histologically necrotizing sialometaplasia may mimic malignant lesions. In the above presented case, the patient's ...

Community-acquired methicillin-resistant Staphylococcus aureus is the first cause of skin and soft tissue infections, but can also produce severe diseases such as bacteremia, osteomyelitis and necrotizing pneumonia. Some S. aureus lineages have been described in cases of necrotizing pneumonia worldwide, usually in young, previously healthy patients. In this work, we describe a fatal case of nec...

A 20 year old woman with anorexia nervosa and severe weight loss developed extensive necrotizing colitis after being admitted to hospital for stabilization of her weight. Necrotizing colitis with anorexia nervosa has been reported previously. We report a second case. We believe necrotizing colitis is a true complication of anorexia nervosa and should be considered in the differential diagnosis ...

We present a case of necrotizing vasculitis with the testicle as the isolated affected organ. A 25-year-old man, pretreated for epididymo-orchitis, presented with a presumed testicular neoplasm. Radical orchiectomy was performed and diagnosis of necrotizing vasculitis was established. In the absence of any other sign of systemic disease, the diagnosis of isolated necrotizing vasculitis of the t...

Inflammatory myopathies such as dermatomyositis and polymyositis are well-recognized paraneoplastic syndromes. Little is known, however, about necrotizing myopathies in association with cancer. We here describe a case of paraneoplastic necrotizing myopathy with a mild inflammatory infiltrate in a patient with adenocarcinoma. After the rapid development of a severe, disabling muscle weakness, th...

Purpose In this report we record the first surgically induced Necrotizing Scleritis case related to trabeculectomy with the use of Ologen Collagen Matrix Implant. Observations Surgically induced Necrotizing Scleritis is a rare pathological entity that complicates ocular (sclera) surgery. Conclusions and importance Prompt management of surgically induced Necrotizing Scleritis related to trab...

BACKGROUND Early recognition and treatment are important factors that can help improve survival following necrotizing fasciitis. However, early recognition is complicated by the difficulty in distinguishing the infection from other, less serious soft-tissue infections such as cellulitis. We reviewed the charts of children presenting with necrotizing fasciitis at a tertiary care pediatric hospit...

We present a case of necrotizing fasciitis diagnosed in the emergency department. The clinical presentation and diagnostic findings of necrotizing fasciitis are discussed.