conclusion: in this study group, tnf-α -238 polymorphism was shown to be different in preeclamptic and non-preeclamptic pregnant women. the aa genotype and the a allele may carry an increased risk for developing of preeclampsia. results: there were significant differences between the two groups in tnf-α genotype at position -238 (p < 0.001). in the preeclamptic group, the frequency of the aa ge...

background: despite the emerging evidence on beneficial effects of probiotics on the cardiovascular system, their impact on the management of ischemic heart diseases and its possible mechanism have not been elucidated. methods: four viable probiotics bacterial strains, including bifidobacterium breve, lactobacillus casei, lactobacillus bulgaricus and lactobacillus acidophilus, at the concentrat...

copper (cu) is an essential trace element involved in normal reproduction but its over-exposure may produce some detrimental effects. the aim of this study was to investigate the effects of purslane on copper sulfate poisoning on liver structures changes. twenty eight wistar rats were randomly allocated to four treatment groups. group i) control, group ii) copper sulfate (200 mg/kg bw were appl...

due to an adenocarcinoma of the right upper lobe with infiltration of the main bronchus a 49-years-old female patient underwent an upper bilobectomy with sleeve resection. after two completed chemotherapy bouts and signs of sepsis another thoracotomy was inevitable.  as a complicating factor a supracarinal, necrotic and perforating lesion of the trachea appeared. the defect can be initially rep...

background:  levels of anti-inflammatory cytokines in blood have a positive relationship with congenital heart disease (chd). we sought to assess the difference in serum cytokines levels between children with and without chd.  methods:  we recruited 60 patients with chd and 30 healthy children, from 2013 to 2014. patients with primary pulmonary hypertension; metabolic diseases; renal, endocrine...

background: probiotics are microorganisms that may influence brain function via altering brain neurochemistry. new research evidence suggests that probiotic bacteria might protect tissue damage through diminishing the production of free radicals and/or inflammatory cytokines. therefore, this study was designed to evaluate the effects of probiotic bacteria on the prevention or reduction of brain...

a case of mycobacterium marinum infection of the nasal cavity is described. a 57 years old man was being on infliximab for 2 years for severe psoriasis presented with five months history of epistaxis, nasal blockage and snoring. local examination revealed bilateral nasal mass. the diagnosis of mycobacterial infection was suspected based upon the histopathological finding of granuloma in the bio...

background: the role of mesenchymal stem cell in cellular therapy is the subject of interest for many researchers. the differentiation potential of mscs and abilities in modulations of the recipient’s immune system makes them important cells in tissue regenerative studies. mscs by releasing the proinflammatory cytokines play important role in immunomodulatory systems; however the signaling path...

background: preeclampsia is a disorder unique to pregnancy and has long been recognized as an important contributor of maternal and fetal morbidity and mortality. it is suggested that cytokines such as tumor necrosis factor-alpha (tnf-α) have an important role in the pathogenesis of preeclampsia and may cause generalized endothelial dysfunction. objective: the aim of this study was comparison o...