Neu differentiation factor (NDF)-induced signaling involves the activation of members of the ErbB family of receptor tyrosine kinases. Although ectopic expression of recombinant ErbB receptors has yielded valuable insight into their signaling properties, the biological function and in vivo interplay of these receptors are still poorly understood. We addressed this issue by studying NDF signalin...

BACKGROUND The Adverse Event Reporting System (AERS) is an FDA database providing rich information on voluntary reports of adverse drug events (ADEs). Normalizing data in the AERS would improve the mining capacity of the AERS for drug safety signal detection and promote semantic interoperability between the AERS and other data sources. In this study, we normalize the AERS and build a publicly a...

This study was conducted to investigate the effect of dextrose, starch, NDF, and a carbohydrate (CHO) mix on utilization of ruminal ammonia in dairy cows. Four ruminally and duodenally cannulated Holstein cows (BW = 788 +/- 31 kg; 217 +/- 35 d in milk) were allocated to four treatments in a 4 x 4 Latin square design trial. Cows were fed an all alfalfa diet at 12-h intervals (DMI = 22.2 +/- 0.25...

The objective of this study was to investigate the effect of NDF content in highly digestible grass/clover silage on particle size reduction, ruminal stratification, and selective retention in dairy heifers. The reduction in particle size from feed to feces was evaluated and related to feed intake, chewing activity, and apparent digestibility. Four grass/clover harvests (Mixtures of Lolium pere...

Dry matter intake (DMI) is related to dietary NDF content (Mertens, 1987) and in vitro NDF digestibility (NDFD, % of NDF; Oba and Allen, 1999). The NRC (2001) summative energy equation is based on fiber digestibility calculated using lignin. Whole-plant lignin content was found to have a strong negative relationship with in-vitro NDFD within comparisons of brown midrib (bm3) hybrids to isogenic...

This study investigated the amount of energy available to growing pigs from fermentation of dietary fiber in the hindgut. Eighteen growing barrows, fitted with a simple T-shaped cannula at the terminal ileum, were allocated to 3 experimental diets in a completely randomized design. The 3 diets were a standard-fiber diet (SFD), which contained 75.1 g NDF/kg diet; a medium-fiber diet (MFD) of 105...

The objective of this experiment was to evaluate the effects of replacing coastcross hay NDF by soybean hull (SH) NDF on the lactation performance and eating behavior of ewes and also on the performance of their lambs. Fifty-six Santa Inês lactating ewes (56.1 +/- 6.8 kg of initial BW; mean +/- SD) were penned individually and used in a randomized complete block design with 14 blocks and 4 trea...

Résumé. Dans ce papier, nous proposons une approche de détection de nouveauté fondée sur les opérateurs de projection orthogonale et l’idée de double bootstrap (bibootstrap). Notre approche appelée Random Subspace Novelty Detection Filter (RS-NDF), combine une technique de rééchantillonnage et l’idée d’apprentissage d’ensemble. RS-NDF est un ensemble de filtres NDF (Novelty Detection Filter), i...

Prediction of carbohydrate fractions using equations from the Cornell Net Carbohydrate and Protein System (CNCPS) is a valuable tool to assess the nutritional value of forages. In this paper, these carbohydrate fractions were predicted using data from three sunflower (Helianthus annuus L.) cultivars, fresh or as silage. The CNCPS equations for fractions B2 and C include measurement of ash and p...

Seven legume straws (Cicer arietinum, Vicia benghalensis, Vicia sativa, Vicia villosa, Vicia faba, Lens culinaris and Pisum sativum) were studied in rumen-cannulated rams. The chemical composition of the studied legume straws varied from 4.3 to 10.1% for ash, 6.1 to 11.4% for CP, 58.0 to 76.5% for NDF, 40.3 to 59.6% for ADF and 8.2 to 14.2% for ADL. Extent of degradation for DM and NDF by the n...