نتایج جستجو برای: ncl

تعداد نتایج: 963  

2002
R. I. McKay Hussein A. Abbass

Anti–correlation has been used in training neural network ensembles. Negative correlation learning (NCL) is the state of the art anti–correlation measure. We present an alternative anti–correlation measure, RTQRT–NCL, which shows significant improvements on our test examples for both artificial neural networks (ANN) and genetic programming (GP) learning machines. We analyze the behavior of the ...

Journal: :Acta Facultatis Medicae Naissensis 2022

Aim: Lung cancer is the leading cause of mortality from across world. In this study, use serum nucleolin (NCL) and nucleophosmin (NPM1) levels as a marker in diagnosis, prognosis treatment response evaluation lung was investigated. Materials Method: NCL NPM1 samples taken before chemotherapy after 3-4 courses control group patients diagnosed with were studied using ELISA method. Results: Serum ...

Journal: :Human molecular genetics 2014
Xenia Lojewski John F Staropoli Sunita Biswas-Legrand Alexandra M Simas Larissa Haliw Martin K Selig Scott H Coppel Kendrick A Goss Anton Petcherski Uma Chandrachud Steven D Sheridan Diane Lucente Katherine B Sims James F Gusella Dolan Sondhi Ronald G Crystal Peter Reinhardt Jared Sterneckert Hans Schöler Stephen J Haggarty Alexander Storch Andreas Hermann Susan L Cotman

Neuronal ceroid lipofuscinosis (NCL) comprises ∼13 genetically distinct lysosomal disorders primarily affecting the central nervous system. Here we report successful reprograming of patient fibroblasts into induced pluripotent stem cells (iPSCs) for the two most common NCL subtypes: classic late-infantile NCL, caused by TPP1(CLN2) mutation, and juvenile NCL, caused by CLN3 mutation. CLN2/TPP1- ...

2007
MOTOTSUNE NAKAHODO CHIKATOSHI YAMADA YASUNORI NAGATA

In this article threshold gates with hysteresis using neuron MOS (νMOS) are presented as basic elements in Null Convention Logic (NCL) circuits. NCL, which proposed by K. M. Fant and S. A. Branst, needs special gates having hysteresis, because NCL uses different ternary logic systems in computation phase and wiping phase of asynchronous behavior, respectively. To impliment the dinamic behavior,...

Journal: :Behavioral neuroscience 2000
B Diekamp T Kalt A Ruhm M Koch O Güntürkün

Dopamine (DA) is known to modulate cognitive functions of the prefrontal cortex (PFC) of mammals, especially via D1 receptor mechanisms. Like the PFC, the neostriatum caudolaterale (NCL) of birds is characterized by dopaminergic input, and NLC and PFC lesions cause similar deficits. The significance of DA in a color discrimination reversal was assessed by evaluating the effects of bilateral inf...

Journal: :Molecular and cellular biology 2011
Kumiko Tominaga Subramanya Srikantan Eun Kyung Lee Sarah S Subaran Jennifer L Martindale Kotb Abdelmohsen Myriam Gorospe

The RNA-binding protein (RBP) nucleolin promotes the expression of several proliferative proteins. Nucleolin levels are high in cancer cells, but the mechanisms that control nucleolin expression are unknown. Here, we show that nucleolin abundance is controlled posttranscriptionally via factors that associate with its 3' untranslated region (3'UTR). The RBP HuR was found to interact with the nuc...

Journal: :Neurocomputing 2009
Ke Tang Minlong Lin Fernanda L. Minku Xin Yao

Negative correlation learning (NCL) is a successful approach to constructing neural network ensembles. In batch learning mode, NCL outperforms many other ensemble learning approaches. Recently, NCL has also shown to be a potentially powerful approach to incremental learning, while the advantages of NCL have not yet been fully exploited. In this paper, we propose a selective NCL (SNCL) algorithm...

2003
J. Ross Macdonald

A complex quantitative model for nearly constant loss ~NCL! is proposed based on an effective-medium approach. Unlike previous NCL response models, it satisfies the Kronig–Kramers transform relations. Here the effective-medium dielectric-level model depends directly on the concentration of mobile charge present and its complex dielectric response is identified as arising from electrical interac...

2000
Sven Kröner Onur Güntürkün Kurt Gottmann

The avian caudolateral neostriatum (NCL) was first identified on the basis of its dense dopaminergic innervation. This fact and data from lesion studies have led to the notion that NCL might be the avian equivalent of prefrontal cortex (PFC). A key feature of the PFC is the ability to integrate information from all modalities needed for the generation of motor plans. By using anteroand retrogra...

Journal: :Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 2013

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