1Pharmacology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt 2Pathology Department, Faculty of Veterinary Medicine, Suez Canal University, Ismailia 41522, Egypt 3Pharmacology Department, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt 4Pharmacology and Toxicology Division, Department of Veterinary Sciences, University of Pisa, Pisa, Italy ...

conclusions totally, our results showed nanosilver caused an increase of at least nine-fold in inhibitory effect of fluconazole. materials and methods we studied effect of fluconazole, nanosilver, and their combination on 20 fluconazole-resistant c. albicans from two centers and one standard sample (atcc10261) by minimal inhibitory concentration (mic) method. background opportunistic fungi caus...

The presence of energetic materials (used as explosives and propellants) at contaminated sites is a growing international issue, particularly with respect to military base closures and demilitarization policies. Improved understanding of the ecotoxicological effects of these materials is needed in order to accurately assess the potential exposure risks and impacts on the environment and its eco...

Many bioactive natural products are derived from traditional Chinese medicine. Some of them showed good treatment potential in tumor chemotherapy. However, limited by the poorly solubility and non-selective toxicity most products, their antitumor efficacy could not be further applied clinicals. Nano-drug delivery systems provided platforms for treatment, many microenvironment-responsive nano-de...

Since food plants are mixtures of large numbers of chemical compounds and since any substance is toxic in a high enough dose, it is not surprising that natural food plants are toxic under certain conditions. Toxicity from common natural foods has resulted from long-term consumption of a single food item or from short periods of consumption of foods containing unusually high levels of a toxic su...

recently, some natural products have been used in the fields as alternative to synthetic compounds, to minimize the negative impacts to the environment. this study aimed to verify the effects of neem-based bio-pesticide in causing acute toxicity for a fish and chronic toxicity for a microcrustacean. to this end, danio rerio and daphnia magna were exposed to various concentrations of a neem-base...

The effects of coastal acidification on the growth and toxicity of the saxitoxin-producing dinoflagellate Alexandrium fundyense were examined in culture and ecosystem studies. In culture experiments, Alexandrium strains isolated from Northport Bay NY, USA, and the Bay of Fundy, Canada, grew significantly faster (16 -190%; p<0.05) when exposed to elevated levels of pCO2 (~ 800- 1900μatm) compare...

Biofouling, an undesirable accumulation of organisms on sea-immersed structures such as ship hulls and fishing nets, is a serious economic issue whose effects include oil wastage and clogged nets. Organotin compounds were utilized since the 1960s as an antifouling material; however, the use of such compounds was later banned by the International Maritime Organization (IMO) due to their high tox...

Background: Although various surface disinfectants have been introduced, most of them are toxic. The use of natural antimicrobial agent e.g. phytol, extracted from Leptadenia pyrotechnica is a new strategy. The aim of this study was to evaluate the antimicrobial activity, toxicity, and stability of phytol. Methods: The serial concentrations of phytol were prepared, and separately incubated with...