Proteins are found to be involved in interaction with solid surfaces in numerous natural events. Acidic proteins that adsorb to crystal faces of a biomineral to control the growth and morphology of hard tissue are only one example. Deducing the mechanisms of surface recognition exercised by proteins has implications to osteogenesis, pathological calcification and other proteins functions at the...

Dental implantology is a field, which has made a great progression recently. The main task nowadays is to shorten the healing period and so improve the comfort for the patients. One possibility how to full fil this task is to coat the surface of the implant. Very promising material seems to be hydroxyapatite, which is a natural component of human body and suitable method is the pulsed laser dep...

In this study the bioactivity of hydroxyapatite/poly(ε-caprolactone)–poly(ethylene glycol) bilayer coatings on Nitinol superelastic alloy was investigated. The surface of Nitinol alloy was activated by a thermo-chemical treatment and hydroxyapatite coating was electrodeposited on the alloy, followed by applying the polymer coating. The surface morphology of coatings was studied using FE-SEM and...

Abstract The investigated cast Ni50–Ti50 shape memory alloy was prepared using a vacuum arc furnace. samples were subjected to in-vitro biocompatibility studies according ISO 10993-12:2004, and compared other Ni–Ti orthodontic wires commercially available at the dental market. hydroxyapatite-coated electrodeposition technique. effect of surface treatment on coating quality addressed. electroche...

Objecttive(s): Despite the poor mechanical properties of hydroxyapatite, its unique biological properties leads we think about study on improving its properties rather than completely replacing it with other biomaterials. Accordingly, in this study we introduced hydroxyapatite reinforced with hardystonite as a novel bio-nanocompositeand evaluate its in-vitro bioactivity with the aim of developi...

In bone disorders infections are common. The concentration of majority of antibiotics is very low in the bone tissue. A high local dose can be obtained from the ciprofloxacin-loaded hydroxyapatite nanoparticles. The present study is aimed at developing the use of hydroxyapatite and zinc-doped hydroxyapatite nanoparticles as a carrier for ciprofloxacin drug delivery system. The ciprofloxacin-loa...

In this study, acicular nano-hydroxyapatite (n-HA) was used to make a new biomimetic composite with polyamide (poly hexamethylene adipamide) by a unique technique. The physical and chemical characteristics of the composites were tested. It was found that these synthesized n-HA crystals were similar to bone apatite in size, phase composition and crystal structure. The biomimetic n-HA crystals we...

BACKGROUND Ceramic hydroxyapatites and non-ceramic hydroxyapatites have been used extensively as alloplastic materials for bone reconstruction. However, different forms of hydroxyapatite induce different types of tissue response. METHODS Human gingival fibroblasts (FMM1 cells) were used to analyze ceramic and non-ceramic hydroxyapatite biocompatibility. The cells were grown on surfaces covere...

Urinary KIM-1 is an ideal biomarker for acute kidney injury diagnosis. The proof-of-concept is demonstrated by utilizing the hydroxyapatite derived from natural fish scales as an electrode material, where the sensing of KIM-1 is shown to be possible for the first time with a linear range from 0.01 to 0.20 μg mL(-1) and a detection limit of 0.017 μg mL(-1) under model conditions; proof-of-concep...

Hydroxyapatite (Ca10(PO4)6(OH)2) is one of the implants materials with medical applications due to its higher biocompatibility. The hydroxyapatite found complete utilization after proper preparation of composite. The influence of zirconia (ZrO2) on the phase composition and on mechanical properties of hydroxyapatite-zirconia composites has been previous investigated and reported. Hierarchical c...