introduction: the aim of this study was to evaluate the effects of aerobic exercise on brain natriuretic peptide (bnp) and c-reactive protein (crp) levels in women with cardiovascular diseases. materials and methods: in this semi experimental study, thirty female patients with at least one coronary artery stenosis (more than70%) were chosen and divided into two groups of aerobic training (n=15)...

Background: Acute respiratory distress (ARD) is a critical respiratory failure due to lung injury of neonates leading to the clinical appearance of poor lung compliance. The aimed of the study was to evaluate the diagnostic values in differentiating respiratory from heart diseases with using of N-terminal pro brain natriuretic peptide (NT-pro BNP) and Atrial natriuretic peptide(ANP) in neonates...

Asthma is a chronic inflammatory disease, characterized by reversible airflow obstruction and airway hyperresponsiveness. There has been a sharp increase in the prevalence, morbidity, mortality and economic burden associated with this disorder over the last several decades, which triggers the development of various antiasthmatic agents [1]. Maintenance of airway tone is the key in asthma therap...

Natriuretic peptides and the reninangiotensin-aldosterone system (RAAS) have reciprocal effects at multiple sites and in varied situations. They interact in health and cardiovascular disease to influence renal, endocrine, and haemodynamic function and cardiovascular cell growth. The atrial natriuretic peptide (atrial natriuretic factor, ANF) discovered by De Bold in 19811 was cloned and sequenc...

1. C-type natriuretic peptide is a neuropeptide, which is also produced by the vascular endothelial cells. Plasma immunoreactive C-type natriuretic peptide concentrations in patients with various diseases have not yet been studied. 2. Plasma immunoreactive C-type natriuretic peptide concentrations were studied by radioimmunoassay in normal subjects, patients with congestive heart failure, non-d...

The proliferation of vascular endothelial cells (EC) is an important event in angiogenesis. The synthesis of the EC growth factor, vascular endothelial cell growth factor (VEGF), is stimulated by a variety of activators; but the effects of important vasoactive peptides are not well understood, and there are no known natural inhibitors of VEGF production. We found that the vasoactive peptides en...

1. Brain natriuretic peptide is a new natriuretic hormone with striking similarity to atrial natriuretic peptide, but there are no previous data concerning its clearance in man. Two pathways of clearance for atrial natriuretic peptide are recognized: degradation by neutral endopeptidase and binding to atrial natriuretic peptide clearance receptors. We have examined the effect of candoxatril, an...

Wong PC, Guo J, Zhang A. The renal and cardiovascular effects of natriuretic peptides. Adv Physiol Educ 41: 179–185, 2017; doi: 10.1152/advan.00177.2016.—The landmark report by de Bold et al. in 1981 signified the heart as one of the endocrine organs involved in fluid and salt balance (de Bold AJ, Borenstein HB, Veress AT, Sonnenberg H. Life Sci 28: 89–94, 1981). Atrial natriuretic peptide (ANP...