نتایج جستجو برای: naproxen

تعداد نتایج: 2312  

The solubility of naproxen in binary mixtures of polyethylene glycol 200 (PEG 200) + water at the temperature range from 298.0 K to 318.0 K were reported. The combinations of Jouyban-Acree model + van’t Hoff and Jouyban-Acree model + partial solubility parameters were used to predict the solubility of naproxen in PEG 200 + water mixtures at different temperatures. Combination of Jouyban-Acree m...

2012
Dalia A. Attia

Naproxen sodium is a non steroidal antiinflammatory drug, used in the treatment of inflammatory and degenerative disorders of the musculoskeletal system. It is widely prescribed for the treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout, extra-articular disorders, bursitis, tendonitis, and non articular rheumatic condition. Naproxen sodium has some side effects when...

Journal: :Arthritis Research & Therapy 2007
Susanne G Schäd Andrea Kraus Imme Haubitz Jiri Trcka Henning Hamm Hermann J Girschick

Pseudoporphyria (PP) is characterized by skin fragility, blistering and scarring in sun-exposed skin areas without abnormalities in porphyrin metabolism. The phenylpropionic acid derivative group of nonsteroidal anti-inflammatory drugs, especially naproxen, is known to cause PP. Naproxen is currently one of the most prescribed drugs in the therapy of juvenile idiopathic arthritis (JIA). The pre...

2013
Catherine Datto Richard Hellmund Mohd Kashif Siddiqui

Non-steroidal anti-inflammatory drugs (NSAIDs), such as non-selective NSAIDs (nsNSAIDs) or selective cyclooxygenase-2 (COX-2) inhibitors, are commonly prescribed for arthritic pain relief in patients with osteoarthritis (OA), rheumatoid arthritis (RA), or ankylosing spondylitis (AS). Treatment guidelines for chronic NSAID therapy include the consideration for gastroprotection for those at risk ...

Journal: :Biochemical Society transactions 1990
A V Flannery G N Dalzell A G Stephen R J Beynon

Bovine articular cartilage explants were maintained in culture for 4 days in the presence of 25 units o f IL-1 with 0 (m), 50 ( m ) and 200 ( m ) pg/ml naproxen, and the media were analysed to determine proteoglycan ( a ) and collagenase activity (h). cultures, and this was maintained for subsequent days. Gelatinase activity showed no significant change with 1L-l at any time. TIMP activity show...

Journal: :Rheumatology 1999
J P Pelletier J A Di Battista M Zhang J Fernandes N Alaaeddine J Martel-Pelletier

Fibroblasts from human synovial membranes were cultured with nimesulide, naproxen or dexamethasone. Nimesulide, but not naproxen, showed effects on the glucocorticoid system that may contribute importantly to its anti-inflammatory activity. Nimesulide at therapeutically relevant concentrations induced the intracellular phosphorylation and activation of glucocorticoid receptors, and activated th...

Journal: :Annals of the rheumatic diseases 1990
A S Taha S McLaughlin P J Holland R W Kelly R D Sturrock R I Russell

The synthesis of gastric and duodenal mucosal prostaglandin E2, prostaglandin I2, and thromboxane B2 during a 60 minute incubation of biopsy specimens, the degree of endoscopic and histological damage, and the anti-inflammatory response were all studied after a four week, double blind study of therapeutic doses of two non-steroidal anti-inflammatory drugs, naproxen and etodolac, received by 27 ...

Journal: :Circulation 1985
B Trimarco A Cuocolo D Van Dorne B Ricciardelli M Volpe A De Simone M Condorelli

In chloralose-anesthetized dogs with the left circumflex coronary artery perfused at constant flow, the effects of increasing doses of indomethacin or naproxen on the coronary and systemic hemodynamic responses to a 5 microgram intracoronary injection of nitroglycerin (NTG) were evaluated. The integrated areas of NTG-induced coronary vasodilatation were reduced after administration of indometha...

Introduction: Effective post-operative pain management is one of the problems following root canal treatment. Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most commonly prescribed analgesics in endodontics. The aim of this study was to evaluate the effectiveness of naproxen in controlling pain following root canal treatment in teeth with irreversible pulpitis. Materials and methods: T...

2007
Frederick R. Taylor

• Objective: To examine the effects of early intervention with sumatriptan/naproxen sodium for migraine on functional ability, productivity, and patient satisfaction. • Design: 2 randomized, double-blind, parallel-group studies. • Participants and setting: Migraineurs aged 18 to 65 years at 106 U.S. neurology and headache clinics treated with sumatriptan 85 mg formulated with RT technology/napr...

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