BACKGROUND Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is an infectious zoonotic pathogen causing human infections. These infections, in some cases, can lead to hemolytic uremic syndrome and its life-threatening complications and even death worldwide. The first intimate bacterial adhesion, intimin (I), with its own receptor translocated intimin receptor (Tir) and E. coli secreted protein ...

Tilapia is the world’s most extensively farmed species after carp. It an attractive for aquaculture as it grows quickly, reaching harvest size within six to seven months of production, and provides important source food revenue many low-income families, especially in low- middle-income countries. The expansion tilapia has resulted intensification farming systems, this been associated with incre...

Chronic hepatitis B (CHB), caused by persistent virus (HBV) infection, significantly increases the risk of leading to liver diseases. Despite successful development and implementation HBV prophylactic vaccines for several decades, therapeutic vaccine, a substantially potential strategy eradicate achieve CHB cure, remains great challenge. Herein, we applied flash nanocomplexation (FNC) technolog...

Nanoparticles have multifaceted advantages in drug administration as vaccine delivery and hence hold promises for improving protection of farmed fish against diseases caused by pathogens. However, there are concerns that the benefits associated with distribution of nanoparticles may also be accompanied with risks to the environment and health. The complexity of the natural and social systems in...

Background: Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is an infectious zoonotic pathogen causing human infections. These infections, in some cases, can lead to hemolytic uremic syndrome and its life-threatening complications and even death worldwide. The first intimate bacterial adhesion, intimin (I), with its own receptor translocated intimin receptor (Tir) and E. coli secreted protein...