Background: Ultrasmallsuperparamagnetic iron oxide (USPIO) nanoparticles are used as blood pool contrast agent for magnetic resonance angiography and perfusion imaging. Our aim in this study was to investigate the effect of the two coating types of iron oxide nanoparticles on the relationship between nanoparticles concentration and signal intensity (SI) in T1-weighted MR images.   Methods : D...

Cerium dioxide (CeO2) and silicon dioxide (SiO2) nanoparticles are of widespread use in modern life. This means that human beings are markedly exposed to them in their everyday life. Once passing biological barriers, these nanoparticles are expected to interact with endothelial cells, leading to systemic alterations with distinct influences on human health. In the present study we observed the ...

background: despite the wide range of applications, there is a serious lack of information on the impact of the nanoparticles on human health and the environment. the present study was done to determine the range of dangerous concentrations of iron oxide nanoparticle and their effects on mouse embryonic stem cells. methods: iron oxide nanoparticles with less than 20 nanometers diameter were enc...

In our study, poly(dl-lactide-co-glycolide) (PLGA) nanoparticles loaded with perphenazine (PPH) and chlorpromazine hydrochloride (CPZ-HCl) were formulated by emulsion solvent evaporation technique. The effect of various processing variables, including PLGA concentration, theoretical drug loading, poly(vinyl alcohol) (PVA) concentration and the power of sonication were assessed systematically to...

the present work focuses on preparation and characterization of erythromycin loaded gelatin nanoparticles through nanoprecipitation method. the procedure consists of the increase of the aqueous gelatin solution to the non-solvent phase containing lutherol f127. three different measures of cross-linker and polymer concentration were also examined, and the optimum concentration was found. the mor...

In this study bio-hydrogen and bioethanol were produced from dry biomass of water hyacinth by microbial fermentation under influence of zinc oxide nanoparticles. For fermentative bio-hydrogen production biomass was first pretreated and then saccharified into fermentable sugars by enzymes. Sugars of enzymatic hydrolysis were xylose and glucose with concentration of 9.0% and 8.0% respectively. Fo...

Synthesis of semiconductor nanoparticles with new photophysical properties is an area of special interest. Here, we report synthesis of ZnS nanoparticles in aqueous micellar solution of Cetyltrimethylammonium bromide (CTAB). The size of ZnS nanodispersions in aqueous micellar solution has been calculated using UV-vis spectroscopy, XRD, SAXS, and TEM measurements. The nanoparticles are found to ...

Functionalization of silica surfaces using organo-silanes is highly sensitive to reaction conditions. Silica-coated nanoparticles were functionalized with propyl-sulfonic acid groups (PS) under different synthesis conditions including, various solvents (Ethanol, methanol, acetonitrile, and toluene), water content in the reaction media (0% to 50%), 3-mercaptopropyl-trimethoxysilane concentration...

Chitosan nanoparticles, such as those prepared in this study, may exhibit potential antibacterial activity as their unique character. The purpose of this study was to evaluate the in vitro antibacterial activity of chitosan nanoparticles and copper-loaded nanoparticles against various microorganisms. Chitosan nanoparticles were prepared based on the ionic gelation of chitosan with tripolyphosph...