نتایج جستجو برای: nanomicelles

تعداد نتایج: 226  

2017
Hashem Alsaab Rami M. Alzhrani Prashant Kesharwani Samaresh Sau Sai HS. Boddu Arun K. Iyer

The aim of this study was to develop a novel folate receptor-targeted drug delivery system for retinoblastoma cells using a promising anticancer agent, curcumin-difluorinated (CDF), loaded in polymeric micelles. Folic acid was used as a targeting moiety to enhance the targeting and bioavailability of CDF. For this purpose, amphiphilic poly(styrene-co-maleic acid)-conjugated-folic acid (SMA-FA) ...

Journal: :Artificial Cells, Nanomedicine, and Biotechnology 2018

2015
Yuchen Zhang Xingwang Zhang Hongming Liu Shaohui Cai Baojian Wu

Z-GP-Dox, the FAPα (fibroblast activation protein-α)-based doxorubicin prodrug, demonstrates excellent tumor targeting effects and a favorable toxicokinetic profile. However, the insoluble nature of Z-GP-Dox becomes a significant barrier to drug administration, particularly when it comes to the clinical stage. Here we developed a nanomicelle system to facilitate the systemic delivery of Z-GP-Do...

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