in this study, a set of experiments were conducted to investigate the influence of edta-grafted iron oxide nanoparticles exposure on agronomic traits of sunflower (helianthus annuus) plants. the experiment was implemented by applying nano-fe3o4-edta and fe-edta fertilizers applied through spray or soil amendment. a variety of parameters including aerial organ biomass, number of leaves, plant he...

Stimulated by concerns of potential infective agents in donated blood, commercial enterprises have attempted to develop blood substitutes since the 1900s. After several years of development, a few of the many leads are showing promise. In this article, nanobiotechnological approaches that are now in phase III clinical trials are reviewed, followed by a discussion of how important basic knowledg...

Biological molecules such as deoxyribonucleic acid (DNA) have shown great potential in fabrication and construction of nanostructures and devices. The very properties that make DNA so effective as genetic material also make it a very suitable molecule for programmed self-assembly. The use of DNA to assemble metals or semiconducting particles has been extended to construct metallic nanowires and...

The field of BioNano/Micro System applies both nanotechnology and MEMS (microelectromechanical systems) to solve biological and medical problems as well as biological structures and principles to solve engineering MEMS problems. In this paper, some technical efforts to develop nanobiotechnology, focusing on nanobiosensor, microfluidics and lab-on-a-chip are briefly reviewed. In order to ensure ...

This article evaluates the oversight of drugs and medical devices by the U.S. Food and Drug Administration (FDA) using an integration of public policy, law, and bioethics approaches and employing multiple assessment criteria, including economic, social, safety, and technological. Criteria assessment and expert elicitation are combined with existing literature, case law, and regulations in an in...

This article uses lessons from biotechnology to help inform the design of oversight for nanobiotechnology. Those lessons suggest the following: first, oversight needs to be broadly defined, encompassing not just regulatory findings around safety and efficacy, but also public understanding and acceptance of the technology and its products. Second, the intensity of scrutiny and review should refl...