A variety of nano-carriers, nano-particles, nano-fibers, nano-tubes etc. have displayed greater competence to mimic nanoscale environment for the enzyme as compared to microand macro-environments provided by traditional support carriers that have been commonly employed for enzyme immobilization. The porous structured beads (silica, alginate etc.), membranes and fibers (>100 μm) have some inhere...

Toxicity tests were performed to investigate possible harmful effects on medaka exposed to nano-iron. Dose-dependent decreases of superoxide dismutase (SOD) and increases of malondialdehyde (MDA) were induced in the medaka embryo, suggesting that oxidative damage was induced by nano-iron. For adult medaka, the disturbance of antioxidative balance was observed during the early exposure period ba...

Increased production and use of nanomaterials has led to an ever growing exposure of livingorganisms to these substances. Limited knowledge about possible toxicity of nanomaterialsand their potential to harm living creatures is becoming a serious concern. To address thisproblem, there is a need for development of diagnostic methods enabling effective determinationof potential toxicity of nanoma...

Creating suitable chemical categories and developing read-across methods, supported by quantum mechanical calculations, can be an effective solution to solving key problems related to current scarcity of data on the toxicity of various nanoparticles. This study has demonstrated that by applying a nano-read-across, the cytotoxicity of nano-sized metal oxides could be estimated with a similar lev...

Nano ZnO is currently used in the rubber, electronics, electrical appliances, enamel, cosmeticsand medical industry. Whereas most studies have used the ecological toxicity of nanoparticles, the toxic effects of nanoparticles in diet is not extensively explored. Because the algaeare at the base of the food chain, any change in their density, biomass and population, wouldaffect the food chain in ...

An electrochemical 'Lab-on-a-chip' for water toxicity detection is presented. This miniaturized device containing an array of nano liter electrochemical cells, which integrates bacteria and can emulate physiological reactions in response to different chemicals. Bacteria, which have been genetically engineered to respond to environmental stress, act as a sensor element and trigger a sequence of ...

AIM Biomimetic nano-assembly formation offers a convenient and bio friendly approach to fabricate complex structures from simple components with sub-nanometer precision. Recently, biomimetic (employing microorganism/plants) synthesis of metal and inorganic materials nano-particles has emerged as a simple and viable strategy. In the present study, we have extended biological synthesis of nano-pa...

The present study shows the advantages of liposome-based nano-drugs as a novel strategy of delivering active pharmaceutical ingredients for treatment of neurodegenerative diseases that involve neuroinflammation. We used the most common animal model for multiple sclerosis (MS), mice experimental autoimmune encephalomyelitis (EAE). The main challenges to overcome are the drugs' unfavorable pharma...