In this work, we present a computational methodology for predicting the change in signal (conductance sensitivity) of a nano-BioFET sensor (a sensor based on a biomolecule binding another biomolecule attached to a nano-wire field effect transistor) upon binding its target molecule. The methodology is a combination of the screening model of surface charge sensors in liquids developed by Brandbyg...

Copper nanoparticles are being applied in the biosensors, engineering, electronic devices, and technology fields. A key advantage of nanomaterials is that their properties differ from bulk with same composition. However, application nano-copper particles for jewelry artwork has not yet been revealed. We discovered compared nano-sized copper fabrication micro-copper particles. The nano- micro-si...

Advances in nanotechnology have made it possible recent years to develop strategies for rapid and sensitive detection of pathogenic bacteria using new nanomaterials the development electronic nano-sensors. The still faces problems such as long analysis time complexity process. An alternative method is use biosensors, which combines a biological recognition mechanism with physical transduction t...

We describe a conductance-based biosensor that exploits DNA-mediated long-range electron transport for the label-free and direct electrical detection of DNA hybridization. This biosensor platform comprises an array of vertical nano-gap biosensors made of gold and fabricated through standard photolithography combined with focused ion beam lithography. The nano-gap walls are covalently modified w...

Nano-bioelectronics represents a rapidly expanding interdisciplinary field that combines nanomaterials with biology and electronics and, in so doing, offers the potential to overcome existing challenges in bioelectronics. In particular, shrinking electronic transducer dimensions to the nanoscale and making their properties appear more biological can yield significant improvements in the sensiti...

Optical energy can be harnessed on the nanoscale by exploiting plasmonic resonances in metallic nanostructures. These resonances are the result of the unique optical properties of metals and their abundance of conduction electrons. Utilizing these properties, it is possible to engineer metallic nano-devices that operate with large electric field intensities confined in and around the structure....

Guanine-rich nucleic acids can form G-quadruplexes that are important in gene regulation, biosensor design and nano-structure construction. In this article, we report on the development of a nanopore encapsulating single-molecule method for exploring how cations regulate the folding and unfolding of the G-quadruplex formed by the thrombin-binding aptamer (TBA, GGTTGGTGTGGTTGG). The signature bl...

Development of nanotechnology during last few decades gave significant contribution to different areas of research especially in biomedical sciences and improved characteristics of many biomaterials allowing their commercial application [1,2]. One of the representative examples is the development of nanomedicine, a new field of medical research which opened the possibility for interactions betw...

Ultrasensitive biosensing is currently a growing demand that has led to the development of numerous strategies for signal amplification. In this context, the unique properties of magnetic particles; both of nano- and micro-size dimensions; have proved to be promising materials to be coupled with disposable electrodes for the design of cost-effective electrochemical affinity biosensing platforms...