The author summarized research on the nadir experience, the experience of one of the very lowest points of life. Although a sense of disintegration, powerlessness, and emptiness marks its immediate aftermath, survivors of rape, bereavement, and maritime disasters have shown that a nadir experience can also be an opportunity for personal transformation and psychological growth. Severe trauma is ...

An effective method for detecting computer misuse is the automatic monitoring and analysis of on-line user activity. During the past year, Los Alamos 1 enhanced its Network Anomaly Detection and Intrusion Reporter (NADIR) to include analysis of user activity on Los Alamos' UNICOS Crays. In near real-time, NADIR compares user activity to historical profiles and tests activity against expert rule...

OBJECTIVE To evaluate the frequency of subclinical acromegaly (in the absence of clinical phenotype but biochemically uncontrolled) in patients with prolactinoma during treatment with dopaminergic agonists. SUBJECTS AND METHODS One hundred twenty one patients without a phenotype suggestive of acromegaly were studied. RESULTS Initially, the laboratory diagnosis of acromegaly was unequivocal ...

The objective of this study was to determine whether the nadir value of serum prostate-specific antigen (PSA) measured by an ultrasensitive assay could be a useful predictor of biochemical recurrence after radical prostatectomy for clinically localized prostate cancer. This study included 127 patients who underwent radical prostatectomy for clinically localized prostate cancer without neoadjuva...

Joubert sendromu anormal solunum paterni, hipotoni, ataksi, serebellar vermis hipoplazisi, gelişim geriliği, oküler anomaliler, renal kistler ve hepatik fibrozis ile karakterize otozomal resesif geçişli nadir bir siliopatidir. Kraniyal manyetik rezonans görüntüleme (MRG) bulgularında molar diş görünümü sendromunun tanısında önemli bulgudur. karakteristik klinik radyolojik bulgularının farkında ...