We construct an incidence structure using certain points and lines in finite projective spaces. The structural properties of the associated bipartite incidence graphs are analyzed. These n×n bipartite graphs provide constructions of C6-free graphs with Ω(n4/3) edges, C10-free graphs with Ω(n6/5) edges, and Θ(7, 7, 7)-free graphs with Ω(n8/7) edges. Each of these bounds is sharp in order of magn...

Aminoacetylation of lysine residues and the modification of arginine by 1,2-cyclohexanedione to N7,N8-(dihydroxy-1,2-cyclohexylidene)arginine were used for probing the surface topology of hen-eggwhite lysozyme as a model protein. The molecular identification of lysine and arginine modification sites was provided by molecular weight determinations of modified and unmodified tryptic peptide mixtu...

1. Using protein-separative chromatographic procedures and assays specific for putrescine oxidase and spermidine oxidase, adult bovine serum was found to contain a single polyamine-degrading enzyme with substrate preferences for spermidine and spermine. Apparent Km values for these substrates were approx. 40 microM. The apparent Km for putrescine was 2 mM. With spermidine as substrate, the Ki v...

The Traveling Salesman Problem (TSP) is the problem of finding a least-cost sequence in which to visit a set of cities, starting and ending at the same city, and in such a way that each city is visited exactly once. Interest in this problem cuts across several fields of study in Business, Economics, Engineering, and Computer Science, due partly to the wide applicability of the problem in practi...

Photoinitiated unimolecular decomposition rate constants of rotationally excited NO2 molecules have been measured near dissociation threshold (D0) by employing a double resonance technique. Rotational selectivity has been achieved by using narrow-linewidth ~0.015 cm! infrared excitation to prepare specific rotational levels (N851,3,...,15, Ka850) of the ~1,0,1! vibrational level. The picosecond...

Neuronal dysfunction and demise together with a reduction in neurogenesis are cardinal features of Alzheimer's disease (AD) induced by a combination of oxidative stress, toxic amyloid-β peptide (Aβ) and a loss of trophic factor support. Amelioration of these was assessed with the Aβ lowering AD experimental drugs (+)-phenserine and (-)-phenserine in neuronal cultures, and actions in mice were e...

Arabidopsis thaliana KORRIGAN1 (KOR1) is an integral membrane endo-β1,4-glucanase in the trans-Golgi network and plasma membrane that is essential for cellulose biosynthesis. The extracellular domain of KOR1 contains eight N-glycosylation sites, N1 to N8, of which only N3 to N7 are highly conserved. Genetic evidence indicated that cellular defects in attachment and maturation of these N-glycans...

Liu, Xibao, Eduardo Rojas, and Indu S. Ambudkar. Regulation of KCa current by store-operated Ca21 influx depends on internal Ca21 release in HSG cells. Am. J. Physiol. 275 (Cell Physiol. 44): C571–C580, 1998.—This study examines the Ca21 influx-dependent regulation of the Ca21-activated K1 channel (KCa) in human submandibular gland (HSG) cells. Carbachol (CCh) induced sustained increases in the...

H3 subtype influenza A virus is one of the main subtypes that threats both public and animal health. However, the evolution and pathogenicity of H3 avian influenza virus (AIV) circulating in domestic birds in China remain largely unclear. In this study, seven H3 AIVs (four H3N2 and three H3N8) were isolated from poultry in live poultry market (LPM) in China. Phylogenetic analyses of full genome...