∗This work has been supported in part by DFG Sonderforschungsbereich Transregio 9, Computergestützte Theoretische Teilchenphysik, by Studienstiftung des Deutschen Volkes, by the Austrian Science Fund (FWF) grants P20347N18, P22748-N18 and SFB F50 (F5009-N15), by the EU Network LHCPHENOnet PITN-GA-2010-264564, by the Reserach Center ‘Elementary Forces and Mathematical Foundations (EMG) of J. Gut...

1998 American Society of Animal Science. All rights reserved. Figure 1. The protein coding sequence from a 2.3-kb nested deletion product of a 4.6-kb HindIII fragment is given. The amino acid translation is shown below the sequence and the stop codon is indicated (*). Conserved amino acids for glycosylation (N15), ligand binding (D138, S228, S231, and F331), disulfide bond formation (C131 and ...

The sigG gene of Mycobacterium tuberculosis was disrupted by homologous recombination, and the genes regulated by SigG were examined by real-time reverse-transcription PCR and microarray studies. The SigG consensus promoter recognition sequence was identified as GCGNGT-N15-18-CGANCA. A DeltasigG mutant was found to be more resistant to mitomycin C treatment than the wild-type strain, indicating...

Using highly precise and accurate Monte Carlo simulations of 20,000,000 replications and 102 independent simulation experiments with extremely low simulation errors and total uncertainties, we evaluated the performance of four single outlier discordancy tests (Grubbs test N2, Dixon test N8, skewness test N14, and kurtosis test N15) for normal samples of sizes 5 to 20. Statistical contaminations...

Important progress in our knowledge concerning the biological precursors of hemin was made when Bloch and Rittenberg (1) presented evidence that significant amounts of deuterium are incorporated into the hemin of rats fed deuterioacetic acid. Further advances in this field were made by Shemin and Rittenberg (2-4), who showed that glycine labeled with N15 is utilized as a nitrogenous precursor o...

Averaged responses to loud clicks were recorded in the unrectified and rectified masseter electromyogram (EMG) of 18 healthy subjects. Unilateral clicks (0.1 ms, 3 Hz, 70-100 dB NHL), delivered during a steady masseter contraction, evoked bilateral responses that appeared to consist of 2 components on the basis of threshold, latency, and their appearance in rectified EMG. The lowest threshold r...

Experiments designed to demonstrate balance between the amount of creatine ingested and the amount retained or excreted as creatine and creatinine have so far failed in their purpose. The results of such studies have led to the opinion either that there is an end-product of creatine other than creatinine or that the synthesis of endogenous creatine is retarded by exogenous creatine (1). We have...

Whether T-cell receptors (TCRs) recognize antigenic peptides bound to major histocompatability complex (MHC) molecules through common or distinct docking modes is currently uncertain. We report the crystal structure of a complex between the murine N15 TCR [1-4] and its peptide-MHC ligand, an octapeptide fragment representing amino acids 52-59 of the vesicular stomatitis virus nuclear capsid pro...

1. The uptake of glycine-N(15) by components of cell nuclei was studied. The nuclear components were derived both from tissues with high metabolic rates-mammalian liver, kidney, and pancreas-and from cells with relatively low rates of metabolism-avian erythrocytes and echinoderm sperm. N(15) uptake by nuclear components of liver, kidney, and pancreas was far more rapid than by those of erythroc...