Mustard agents are potent DNA alkylating agents with mutagenic, cytotoxic and vesicant properties. They include bi-functional agents, such as sulfur mustard (SM) or nitrogen mustard (mustine, HN2), as well as mono-functional agents, such as "half mustard" (CEES). Whereas SM has been used as a chemical warfare agent, several nitrogen mustard derivatives, such as chlorambucil and cyclophosphamide...

The role of the quinone group in the antitumor activity of quinone alkylating agents, such as mitomycin C and 2,5-diaziridinyl-3,5bis(carboethoxyamino)-l,4-benzoquinone, is still uncertain. The quinone group may contribute to antitumor activity by inducing DNA strand breaks through the formation of free radicals and/or by influencing the alkylating activity of the quinone alkylators. The cytoto...

in order to study the interaction allelopathic effects of wheat, barley and wild mustard on seed germination and seedling growth, this investigation was conducted in 2009 in two separate experiments. allelopathic effect of four aqueous extracts (0, 2.5, 5 and 10%) of wild mustard on wheat and barley germination was evaluated in the first experiment, based on two randomized completely designs (r...

sulfur mustard is one of the major potent chemical warfare agents. it was widely used against not only military personnel but also civilian people ofiranduring the last years (1984–1988) of the iraq–iran war. a number of studies were performed regarding the acute and long-term consequences of sulfur mustard on respiratory system. currently, many aspects of leading respiratory disorder that was ...

introduction: chronic obstructive pulmonary disease (copd) secondary to sulfur mustard exposure, known as mustard lung, is an important late pulmonary complication. the bode (body mass index, obstruction, dyspnea, and exercise) index has been established as a valuable tool for determining the adverse consequences of copd. the aim of this study was to evaluate the role of the bode index in patie...

Background: Sulfur mustard was the most widely applied chemical warfare agent by the Iraqi army in Iran–Iraq war (1983-1988). Considering the role of sulfur mustard toxicity in hematopoietic neoplasms and also new role of JAK2 mutation in these neoplasms, we assessed this mutation and delayed hematologic complications in veterans exposed to sulfur mustard. Methods: This case control st...

The interaction of sulfur mustard with aminoacids and proteins has been investigated in this study. Rats were injected with sublethal doses of sulfur mustard subcutaneously and intraperitoneally. At different time intervals, plasma and urine samples were collected. The binding affinity of sulfur mustard with urinary and plasma proteins and enzymes was studied for the first time using non-i...

to evaluate the effect of different rates of nitrogen fertilizer on competitive ability of canola (okapi cv.) in interference with wild mustard, a split-plot experiment based on a randomized complete block design with 3 replications was carried out at agricultural faculty of bu-ali sina university, in 2008-2009. 4 levels of nitrogen fertilization (100, 150, 200 and 250 kg n ha-1) were assigned ...

Management of nitrogen fertilization in crops is one of the most important components of integrated weed management. A two-year field experiment was conducted to determine the direct effects of wild mustard aboveground biomass and N content of wild mustard on oilseed rape yield. A set of factorial treatments was arranged in a randomized complete block design with four replications. Treatments w...

Garlic mustard (Alliaria petiolata), a biennial species, is considered to be among the most troublesome of the invasive plants in the Eastern Deciduous forest of North America. It has been shown to prevent or reduce mycorrhizal colonization of native herbaceous ground layer plants and trees in these forests. It is estimated that 70-90% or more of herbaceous native ground layer plant species for...