BACKGROUNDS/AIMS International treatment guidelines for branch duct intraductal papillary mucinous neoplasm (BD-IPMN) of the pancreas have been proposed, for features associated with malignancy and invasiveness. We investigated the clinicopathological characteristics that are predictive of malignancy or invasiveness and disease recurrence. METHODS A review of 324 patients with resected and pa...

PURPOSE We sought to document the appearance of isolated cysticercal infestation of single extraocular muscles on MR and CT studies, and to compare these findings with results of histopathologic examination. METHODS Six MR and three CT examinations of the orbits of six patients were reviewed. Histopathologic confirmation of the diagnosis was available in three patients, and response to specif...

The prevalence of pancreatic cysts has increased significantly over the last decade, partly secondary to quality and frequency cross-sectional imaging. While majority never progress cancer, a small number will need be followed. management can both confusing intimidating due multiple guidelines with varying recommendations. Despite differences in specifics guidelines, they all agree on several h...

background: the mitogen-activated protein kinase (mapk) pathway is one of the major signaling pathways that transmit intracellular signals initiated by extracellular stimuli to the nucleus. the stress-activated protein kinase (sapk)/c-jun nh2-terminal kinase is a subfamily of map kinases implicated in cytokine and stress responses. objective: in this study, we have examined total and phosphoryl...

BACKGROUND Tumor blood vessels are both structurally and functionally abnormal compared with normal vessels. A limited support of mural cells may contribute to these abnormalities. Here, we characterized mural cell recruitment in 2 mouse tumor models and addressed the question of why tumor vessels fail to recruit a proper coat of mural cells. METHODS AND RESULTS We studied mural cell recruitm...

Astroblastoma is a rare glial neoplasm whose histogenesis has been clarified recently. It primarily occurs in children and young adults. We are reporting a case of 12-year-old girl child who presented with features of raised intracranial tension and generalized tonic-clonic seizures. Brain magnetic resonance imaging revealed a large well-circumscribed, cystic lesion without perifocal edema, and...

Neoplasms of the central nervous system (CNS), when examined macroscopically, may be circumscribed or diffusely infiltrating. Circumscribed glial and mixed glial-neuronal neoplasms include, among others, pilocytic astrocytoma (PA), pleomorphic xanthoastrocytoma (PXA) and ganglioglioma (GG). Besides being circumscribed, these neoplasms share several similarities: they affect mostly children, ado...