It has been demonstrated in several model systems that tumors arise in a multistage process. Carcinogenic aromatic amines are complete carcinogens, which usually produce tumors in typical target tissues without any additional treatment. The tissue specificity, however, cannot readily be explained by genotoxic effects, and the role of secondary effects is not well understood. Promotional pressur...

During the multistage fracturing of shale gas horizontal wells, casing damage frequently occurs, making it essential to evaluate stress and deformation. This paper establishes a mathematical model thermo-hydro-mechanical coupling finite element casing-cement sheath-formation (CCF). examines effects temperature, thickness, nonuniform in situ stress, mechanical properties cement sheath, treating ...

In this paper, we develop a multistage approach for estimating the mean of a bounded variable. We first focus on the multistage estimation of a binomial parameter and then generalize the estimation methods to the case of general bounded random variables. A fundamental connection between a binomial parameter and the mean of a bounded variable is established. Our multistage estimation methods rig...

In this paper, we develop a multistage approach for estimating the mean of a bounded variable. We first focus on the multistage estimation of a binomial parameter and then generalize the estimation methods to the case of general bounded random variables. A fundamental connection between a binomial parameter and the mean of a bounded variable is established. Our multistage estimation methods rig...

Turbodrill is a type of hydraulic axial turbomachinery which has a multistage blade consisting of stators and rotors. In this paper, a turbodrill blade that can be applied in crystallized section under high temperature and pressure conditions is developed. On the basis of Euler equations, the law of energy transfer is analyzed and the output characteristics of turbodrill blade are proposed. Mor...

Background. High blood pressure in adults is directly correlated with increased risk of cardiovascular diseases. Hypertension in childhood and adolescence could be considered among the major causes of this problem in adults. This study aimed to investigate the factors associated with hypertension among the adolescents of Jahrom city in Iran and also standard percentiles of blood pressure were e...

Cardiovascular disease has become the first cause of death in Indonesia. The highest morbidity is found in the aged, and among cardiovascular disorders or diseases, the prevalence of hypertension is the highest. Many studies of the relationship between nutritional factors and hypertension have been conducted, especially with reference to the metabolic syndrome, but studies to understand determi...