نتایج جستجو برای: multinodular goiter
تعداد نتایج: 5072 فیلتر نتایج به سال:
Thyroid cancer may have a familial predisposition but a specific germline alteration responsible for the disease has not been discovered yet. We have shown that familial papillary thyroid cancer (FPTC) patients have an imbalance in telomere-telomerase complex with short telomeres and increased telomerase activity. A germline mutation (A339V) in thyroid transcription factor-1 has been described ...
A parathyroid lipoadenoma is a very rare cause of mediastinal mass. The clinical features of this pathologic entity is similar to those of the more common pathologic variants of parathyroid disease associated with primary hyperparathyroidism. A 58-year-old woman presented with huge multinodular goiter. Her thoracic CT scan was done before surgery, showed a posterior mediastinal mass. On microsc...
Medical records of 228 patients who had undergone thyroid surgery were studied. There were 179 females and 49 males with mean age of 33-8 years. Pre-op. diagnosis was cold nodule in 4. 4 %. Pathology diagnosis was simple goiter in 54%, adenoma in 23%, thyroid cancer in 15% and colloid cyst in 5.3% of the patients. Among carcinomas 68% were papillary, 29% follicular and 3% medullary. There were1...
pendred's syndrome is defined as a triad of congenital perceptive hearing loss, goiter, and abnormal perchlorate test. three brothers with pendred's syndrome [p.s.] are reported. the oldest brother has hearing loss (he has been deaf and mute since childhood) and has a large goiter. a thyroid scan revealed euthyroid multinodular goiter and a perchlorate test was performed, and reported...
Thyroid goiter is a common condition that is often associated with iodine deficiency. Familial forms of goiter in areas not known to feature iodine deficiency are much less common. We have performed a genomic search on a single large Canadian family with 18 cases of nontoxic multinodular goiter in which 2 individuals also had papillary lesions highly suggestive of papillary carcinoma. A locus o...
The patient is a 55-year-old female with a history of multinodular goiter. She was followed for several years for a dominant left-sided superior pole thyroid nodule. Several prior fine needle aspiration biopsies had been performed. All were consistent with the diagnosis of degenerative colloid nodule. Eventually she developed symptoms of intermittent choking and shortness of breath and presente...
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