Antibiotic resistance is a worldwide problem of major importance. Isolations in some countries of multi-drug-resistant (resistant to three or more classes of antimicrobials), extensively-drug-resistant (resistant to all but one or two classes) or even pan-drugresistant (resistant to all available classes) Gram-negative pathogens are causing therapeu‐ tic problems andin the same timeare posing i...

Efficacy of Amikacin and Imipenem Against Multi-Drug Resistant Gram-Negative Bacteria Isolated from Wound Infections, Egypt

background hospital patients who are nasal carriers of methicillin-resistant staphylococcus aureus (mrsa) are a high-risk potential threat to themselves and other hospitalized patients. the high antibiotic resistance of these isolates renders the treatment of related infections difficult. objectives the present study, for the first time investigated the prevalence of mrsa isolates in nasal carr...

determination of drug resistance rate, as a new major problem in patients with typhoid fever is inevitable for treatment of the disease. in a cross-sectional study, during march 1994 till february 1995, a total of 39 patients with typhoid fever admitted to dept. of infections diseases, emam khomeini hospital, and were examined for the rate of resistance to routine drugs usually used for treatme...

extensively drug-resistant tuberculosis (xdr-tb) is a new challenge for tuberculosis control programs. lack of effective drugs and high rate of failure in treatment and mortality is a major threat for public health. treatment of this serious infection needs well-designed individualized dosage regimen and powerful national tb program. in this review we will describe the xdr-tb definition and its...

Background: Patient immune status might be indicative of the variance in bacterial genetics in drug-resistant tuberculous pleuritis and could be used for predicting the risk of multi-drug resistant tuberculous pleuritis (MDR-TB). Objective: To determine the significance of Th2/Th1 ratio and concentration of PD-L1 in the pleural effusions for prediction of MDR-T...