Background/introduction An approach of drug delivery to hypovascular tumor tissues is proposed. For such tumor tissues, it is difficult to deliver anti-tumor agents at enough concentration and duration by either systemic or local administration. If we could manipulate the distribution of locally injected drugs by ultrasound, an efficient drug therapy would be possible. We have found that locall...

We describe a multi-color microfluidic dye laser operating in whispering gallery mode based on a train of alternating droplets containing solutions of different dyes; this laser is capable of switching the wavelength of its emission between 580 nm and 680 nm at frequencies up to 3.6 kHz-the fastest among all dye lasers reported; it has potential applications in on-chip spectroscopy and flow cyt...

the evaporation of liquid droplets is of fundamental importance in a large number of practical situations ranging from technological applications such as ink-jet printing, spray cooling and various coating processes, to a variety of biological and geophysical contexts. in this study, the behavior of the surfaces of glass, plexiglas, aluminum and copper in the evaporation of water droplets is st...

Based on the competition between members of a hierarchy of length scales in complex multi-scale systems, it is shown how clustering of active quantities into concentrated sets, like bubbles in a Swiss cheese, is a generic property that dominates the intermittent structure. The halo-like surfaces of these clusters have scaling exponents lower than that of their kernels, which can be as high as t...

This paper describes a multifunctional semi-closed droplet-array chip coupled with electrospray ionization mass spectrometry (ESI-MS) detection for multiple sample pretreatment and analysis. A novel interfacing method for coupling droplet system with ESI-MS was proposed using a sampling probe-two-dimensional (2D) droplet-array strategy. The 2D droplet-array system was composed of an 8 × 8 micro...

The study of the regulatory roles in small RNAs can be accelerated by techniques that permit simple, low-cost, and rapid extraction of small RNAs from a small number of cells. In order to ensure highly specific and sensitive detection, the extracted RNAs should be free of the background nucleic acids and present stably in a small volume. To meet these criteria, we designed a multi-well/multi-ch...

A new algorithm for the auto-selection of quasi-components and components (QC/Cs) in ‘multi-dimensional quasi-discrete’ model is suggested. This applied to analysis heating evaporation multi-component fuel droplets. It allows one automatically select QC/Cs update initial selection during droplet evaporation. The expected be applicable a wide range fuels blends. can directly implemented into CFD...

the paper is focused on the formation of calcium phosphate nanoparticles (cp) in polyelectrolyte-modified microemulsions, in a microemulsion template phase consisting of cyclohexane, water, anionic surfactantant and cosurfactant, in the presence of anionic and cationic polyelectrolyte. it is shown that polyelectrolyte, can be incorporated into the individual inverse microemulsion droplets. the ...

the conversion process of heavy hydrocarbons to the valuable products such as gasoline is an important operation in the oil refineries.one important process is the “fluidized catalytic cracking” (fcc).feed injection in fcc process has an important role in the selectivity and properties of the products.performance of the feed injection system is dependent on the atomizers.the size and contributi...

The growth of a two-phase cloud of a liquid fuel in a stagnant atmosphere is studied using computational fluid dynamic techniques. In order to predict the danger and hazard of such cloud in open atmosphere it is very important to determine the fuel concentration in the cloud, especially in the far field region from the fuel reservoir. The results show that with omission of droplets break up...