The control loop in the Varian DMLC system (V4.8) requires approximately 65 msec to monitor and halt the irradiation of a segment, causing an "overshoot" effect: the segment ends on a fractional monitor unit larger than that planned. As a result, the actual MU delivered may differ from that planned. In general, for step-and-shoot treatments, the first segment receives more, the last receives le...

Buruli ulcer (BU) vaccine design faces similar challenges to those observed during development of prophylactic tuberculosis treatments. Multiple BU vaccine candidates, based upon Mycobacterium bovis BCG, altered Mycobacterium ulcerans (MU) cells, recombinant MU DNA, or MU protein prime-boosts, have shown promise by conferring transient protection to mice against the pathology of MU challenge. R...

A  $ mu $-way  $ G $-trade ($ mu geq 2) $  consists of $ mu $ disjoint decompositions of some simple (underlying) graph $ H $ into copies of a graph $ G. $  The   number of copies of the  graph $ G $ in  each of the decompositions is the volume of the $ G $-trade and   denoted by $ s. $ In this paper, we determine all values  $ s $ for which there exists a $  mu $-way   $ K_{1,m} $-trade of  vo...

The contribution of lymphatic transport to the oral bioavailability of methylnortestosterone (M) after oral administration of the lipophilic prodrug methylnortestosterone undecanoate (MU) has been evaluated, and the sensitivity of lymphatic MU transport to lymphatic lipid transport has been investigated. M and MU were administered intravenously and orally to greyhound dogs to determine absolute...

Transgenic mice were produced that carried in their germlines rearranged kappa and/or mu genes with V kappa and VH regions from the myeloma MOPC-167 kappa and H genes, which encode anti-PC antibody. The mu genes contain either a complete gene, including the membrane terminus (mu genes), or genes in which this terminus is deleted and only the secreted terminus remains (mu delta mem genes). The m...

Linearly ordered tetraphosphine, meso-bis[(diphenylphosphinomethyl)phenylphosphino]methane (dpmppm), readily reacted with 4 equiv. of CuX in dichloromethane to afford octanuclear copper(I) complexes, [Cu(8)(mu-X)(8)(mu-dpmppm)(2)] (X = Cl (1a), Br (1b), I (1c)), which involve a ladder-type {Cu(8)(mu-X)(2)(mu(3)-X)(6)} core supported by two dpmppm ligands in anti arrangement. Complex 1a was furt...

Let $G = {rm Res}_{F/mathbb{Q}}(GL_n)$ where $F$ is a number field‎. ‎Let $S^G_{K_f}$ denote an ad`elic locally symmetric space for some level structure $K_f.$ Let ${mathcal M}_{mu,{mathbb C}}$ be an algebraic irreducible representation of $G({mathbb R})$ and we let $widetilde{mathcal{M}}_{mu,{mathbb C}}$ denote the associated sheaf on $S^G_{K_f}.$ The aim of this paper is to classify the data ...

We report the characterization of a new sodium channel blocker, mu-conotoxin PIIIA(mu-PIIIA). The peptide has been synthesized chemically and its disulfide bridging pattern determined. The structure of the new peptide is: [sequence: see text] where Z = pyroglutamate and O = 4-trans-hydroxyproline. We demonstrate that Arginine-14 (Arg14) is a key residue; substitution by alanine significantly de...

The murine tumor line 70Z/3 resembles a pre-B lymphocyte in containing the heavy chain of IgM (mu) as a cytoplasmic protein in the apparent absence of light chain (L). However, these cells can be induced by lipopolysaccharide to differentiate into a B lymphocyte-like state, containing mu2L2 tetramers as membrane-bound molecules. This is a accompanied by an increase in mu synthesis, the acquisit...

‎a $mu$-way $(v,k,t)$ $trade$ of volume $m$ consists of $mu$‎ ‎disjoint collections $t_1$‎, ‎$t_2‎, ‎dots t_{mu}$‎, ‎each of $m$‎ ‎blocks‎, ‎such that for every $t$-subset of $v$-set $v$ the number of‎ ‎blocks containing this t-subset is the same in each $t_i (1leq‎ ‎i leq mu)$‎. ‎in other words any pair of collections ${t_i,t_j}$‎, ‎$1leq i< j leq mu‎$ is a $(v,k,t)$ trade of volume $m$. in th...