Paulownia tomentosa, used in traditional Chinese medicine, is the treatment of diseases such as bronchitis and asthma thanks to its biological activities. In addition, it known have antimicrobial, antioxidant, anticancer effects also dysentery, gonorrhea, hemorrhoids. this study, antimicrobial activity extracts obtained from methanol solvent flower petal parts P. tomentosa was determined accord...

the purpose of the present study is to investigate the cytotoxicity/apoptotic effect of 2-chloro-2′-deoxyadenosine, cladribine, (2-cda) in the human breast cancer cell line, mda-mb468 (estrogen receptor negative, er−). mtt [3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2h tetrazolium bromide] assay, annexin v-fluorescein/pi and hoechst 33258 staining were used to detect cytotoxicity and cell apopto...

Circular RNAs (circRNAs) play a crucial role in tumor occurrence and progression. And the dysregulated circRNAs are reported to be relevant glioma development. Nevertheless, function regulatory mechanism of hsa_circ_0030018 progression largely indistinct. The abundances hsa_circ_0030018, miR-1297, RAB21 were detected using quantitative real-time polymerase chain reaction or western blot. Cell p...

Objective: Basic fibroblast growth factor (bFGF) plays a pivotal role in cell proliferation, differentiation and extracellular matrix turnover various tissues. In human dental pulp cells (HDPCs), let-7 microRNA is involved proliferation differentiation. There little information on the effect of bFGF-induced HDPCs. This study investigated bFGF let-7g, let-7f, let-7i microRNAs some genes includin...

This study was investigated to evaluate the in vitro anti-diabetic activity and lipid accumulation inhibitory effect of domestic walnut (Junglans regia, Gimcheon 1ho cultivar) high glucose- oleic acid-induced hepatic HepG2 cells. Eighty percent ethanolic extract from (GC) showed higher effects against α-amylase α-glucosidase activities when compared other extracts. GC significantly inhibited fo...

PURPOSE To evaluate the protective effects of Epigallocatechin gallate (EGCG) against UV irradiation in cultured human retinal pigment epithelial (RPE) cells. METHODS UV irradiation was produced by a UV lamp for 30 seconds with an irradiance of 3.3 mW/cm2. After 5 minutes and 1 hour, we administered different concentrations of EGCG (0, 5, 10, 15, 25, 50, 100 uM). The cell count was determined...

BACKGROUND The low proliferative viability of human nucleus pulposus(NP) cells is considered as a cause of intervertebral discs degeneration. Growth factors, such as TGF-beta1 and IGF-1, have been implicated in cell proliferation and matrix synthesis. OBJECTIVE To investigate the dose-response and time-course effect of transforming growth factorbeta1(TGF-beta1) and insulin-like growth factor-...