background: the clinical course of multiple sclerosis (ms) evolves over many years. its prognosis is highly variable among affected individuals, i.e. while some suffer from early severe disabilities, others remain ambulatory and functional for many years. we used multiple sclerosis severity score (msss) and the new classification for ms severity herbert et al. introduced in 2006 according to ms...

GloSea5, a seasonal forecast system of the UK Met Office, shows reasonable skill among state-of-the-art operational systems. However, average surface temperature (T2m) in winter (December–February) GloSea5 is particularly low East Asia. To improve over Asia, we focused on high score global teleconnection patterns simulated by GloSea5. Among well-predicted patterns, selected those highly correla...

The Nyström sampling provides an efficient approach for large scale clustering problems, by generating a low-rank matrix approximation. However, existing sampling methods are limited by their accuracies and computing times. This paper proposes a scalable Nyström-based clustering algorithm with a new sampling procedure, Minimum Sum of Squared Similarities (MSSS). Here we provide a theoretical an...

WMN (Wireless Mesh Network) is usually built on fixed stations and interconnected via wireless links to form a multi-hop network. Typical and inexpensive deployment of WMNs use some MSSs (Mesh Subscriber Station) and one MBS (Mesh Base Station), where their multi-hop feature can be utilized to increase their range of accessibility in rural areas effectively. Moreover, since they are dynamically...

We consider the problem (MSSS) of nding a strongly connected spanning subgraph with the minimum number of arcs in a strongly connected digraph. This problem is NP-hard for general digraphs since it generalizes the hamil-tonian cycle problem. We show that the problem is polynomially solvable for quasi-transitive digraphs. We describe the minimum number of arcs in such a spanning subgraph of a qu...

Multiple Sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system. It is a clinically heterogeneous disorder especially in terms of disease severity. Current investigations suggest that genes and gene-gene interactions not only influence on susceptibility to MS but also affect the disease severity. In this study, we investigated the contribution of the HLADRB1*1501 ...

Bone marrow cultures have been established from mice infected with Mesocestoides corti and undergoing parasitic eosinophilia. In the absence of added conditioned medium, eosinophil differentiation ceases, and eosinophils are undetectable by 7 days, whereas neutrophil production continues over several weeks as with normal bone marrow. Eosinophil production can be induced by adding pokeweed mitog...

The challenge of future mobile multimedia networks is to provide worldwide tetherless communication services. Low Earth Orbit-Mobile Satellite Systems (LEO-MSSs) will play a significant role by filling the coverage gaps of future generation terrestrial cellular networks. This lecture presents research results on demand-assignment Medium Access Control (MAC) schemes able to share efficiently LEO...

BACKGROUND While many factors have been examined, male gender and older age at multiple sclerosis onset are among few variables consistently associated with increased disability. Interestingly, the association between onset age and disability may not be linear with some data suggesting a faster rate of accumulation of disability in patients aged more than 30 years at onset. OBJECTIVE Explore ...