Paracetamol (Acetaminophen) is one of the drugs most often prescribed to patients, ranging from children elderly, as a pain reliever by inhibiting prostaglandin synthesis in central nervous system. has broad therapeutic index with an adult dose 500-1000 mg each time, interval 4-6 hours. The review article aims compare analysis and sample preparation methods used detect paracetamol human blood, ...

This project tries to understand American Graduate Admissions process by specifically analyzing MS Computer Science application over past 5 years. Edulix has been used as data source. After extensive data cleaning, I have tried to model admissions data based on patterns extracted from data and domain knowledge. The key to analyzing Graduate Admissions data is to analyze data in buckets rather t...

The online combination of surface plasmon resonance (SPR) with mass spectrometry (MS) could be beneficial for accurately acquiring molecular interaction data simultaneously with their structural information at high throughputs. In this work, a novel SPR-MS interface was developed using a dielectric barrier discharge ionization (DBDI) source. The DBDI source was placed in front of the MS inlet, ...

The accurate characterization of synthetic polymer sequences represents a major challenge in polymer science. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is frequently used for the characterization of copolymer samples. We present the COCONUT software for estimating the composition distribution of the copolymer. Our method is based on Linear Progr...

We report a new microfluidic emitter for nano-electrospray ionization mass spectrometry (nanoESI-MS), made from polyimide tape. In contrast to the conventional pulled glass capillary emitters typically used for nanoESI-MS, these new polyimide emitters are simple and inexpensive to make, and are disposable after a single use. Thus, sample contamination and clogging are never a problem when analy...

A new centrosymmetric cyclohexapeptide, aspersymmetide A (1), together with a known peptide, asperphenamate (2), was isolated from the fungus Aspergillus versicolor isolated from a gorgonian coral Carijoa sp., collected from the South China Sea. The chemical structure of 1 was elucidated by analyzing its NMR spectroscopy and MS spectrometry data, and the absolute configurations of the amino aci...